# Non-clostridial gas gangrene due to Anaerococcus tetradius following a cesarean section: A case report

**Authors:** Takehiro Hashimoto, Mamiko Okamoto, Tomonori Yamada, Eiji Kobayashi, Kazufumi Hiramatsu

PMC · DOI: 10.1016/j.bjid.2025.104609 · The Brazilian Journal of Infectious Diseases · 2025-12-23

## TL;DR

A 25-year-old woman developed a rare infection after a cesarean section caused by Anaerococcus tetradius, a bacteria not commonly linked to such infections.

## Contribution

This is the first reported case of Non-Clostridial Gas Gangrene caused by Anaerococcus tetradius following a cesarean section in an immunocompetent patient.

## Key findings

- The patient was diagnosed with Non-Clostridial Gas Gangrene due to Anaerococcus tetradius.
- Histopathological examination confirmed skeletal muscle necrosis.
- A. tetradius infections are rare and should be considered in post-cesarean complications.

## Abstract

A 25-year-old healthy woman was admitted to our hospital with fever and abdominal pain. Abdominal contrast-enhanced computed tomography revealed a fluid collection with foamy gas formation extending from both rectus abdominis muscles to the subcutaneous tissue. Antimicrobial therapy with meropenem (3 g/day), clindamycin (1800 mg/day), and daptomycin (300 mg/day) was initiated as empiric therapy. Subcutaneous abscess culture revealed gram-positive cocci, which was identified as Anaerococcus tetradius. Histopathological examination of the necrotic tissue showed skeletal muscle necrosis. On the basis of these findings, the patient was diagnosed with Non-Clostridial Gas Gangrene (NCGG) due to A. tetradius. We report a novel case of NCGG caused by A. tetradius following a cesarean section in an immunocompetent patient. Although A. tetradius has been detected in clinical specimens, cases of human infections are extremely rare. Clinicians should consider A. tetradius infection as a complication of a cesarean section.

## Linked entities

- **Chemicals:** meropenem (PubChem CID 441130), clindamycin (PubChem CID 446598), daptomycin (PubChem CID 21585658)
- **Species:** Anaerococcus tetradius (taxon 33036)

## Full-text entities

- **Diseases:** abdominal pain (MESH:D015746), NCGG (MESH:D005738), muscle (MESH:D019042), fever (MESH:D005334), necrosis (MESH:D009336), abscess (MESH:D000038), A. tetradius infection (MESH:D007239)
- **Chemicals:** daptomycin (MESH:D017576), clindamycin (MESH:D002981), meropenem (MESH:D000077731)
- **Species:** Homo sapiens (human, species) [taxon 9606], Anaerococcus tetradius (species) [taxon 33036]

## Full text

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## References

18 references — full list in the complete paper: https://tomesphere.com/paper/PMC12800404/full.md

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Source: https://tomesphere.com/paper/PMC12800404