# True Impact of Sex Differences in Diagnosis and Management of Cardiovascular Disease

**Authors:** Lana Alamat, Aakash Rana, Angel Lopez Candales, Khalid Sawalha, Allison Shaw-Devine

PMC · DOI: 10.7759/cureus.99237 · Cureus · 2025-12-14

## TL;DR

This review highlights how women face greater risks from cardiovascular disease compared to men and suggests ways to improve outcomes for women.

## Contribution

The paper outlines specific sex differences in CVD diagnosis and management to address disparities in women's outcomes.

## Key findings

- Women experience different CVD manifestations compared to men.
- Current understanding and treatment strategies for CVD are less effective for women.
- Adapting prevention and treatment strategies could reduce disparities in outcomes.

## Abstract

Over the years, scientific advancements have enhanced our understanding of cardiovascular disease (CVD) in adults. Unfortunately, progress has been less substantial in understanding the manifestations of CVD in women. In light of this discrepancy, the goal of this review is to outline specific differences between men and women that appear to place women at increased risk of poorer outcomes from cardiovascular disease compared to their male counterparts. A better understanding of these differences may provide clinicians with an advantage in recognizing potential areas to target for improving outcomes among women. By adapting strategies for both prevention and treatment in this large population, we may help mitigate the longstanding disparities that persist.

## Linked entities

- **Diseases:** cardiovascular disease (MONDO:0004995)

## Full text

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## References

90 references — full list in the complete paper: https://tomesphere.com/paper/PMC12800384/full.md

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Source: https://tomesphere.com/paper/PMC12800384