Pyrethroid insecticide resistance of Aedes albopictus and Aedes aegypti (Diptera: Culicidae) across the Hawaiian Islands
Sangwoo Seok, Miles T. McCollum, Christopher M. Jacobsen, Omar S. Akbari, Derrick K. Mathias, Yoosook Lee

TL;DR
This study examines pyrethroid insecticide resistance in Aedes mosquitoes across the Hawaiian Islands, finding no genetic resistance but early signs of possible phenotypic resistance in some populations.
Contribution
The first report on phenotypic insecticide resistance in Hawaiian Aedes mosquitoes, highlighting early signs of resistance in Ae. albopictus.
Findings
No non-synonymous mutations in the VGSC gene were found, indicating no genotypic resistance to pyrethroids.
Phenotypic assays showed high susceptibility to permethrin in most populations, but some Ae. albopictus showed early resistance signs.
This is the first study to assess pyrethroid resistance in Hawaiian Aedes mosquitoes.
Abstract
Aedes albopictus (Skuse, 1894) and Aedes aegypti (Linnaeus, 1762) (Diptera: Culicidae) are invasive species in the Hawaiian Islands as well as other islands of the Pacific and serve as the primary vectors of arboviruses such as dengue virus. Despite its significance to public health, data on their insecticide resistance remains limited. Knowledge of the level of insecticide resistance is critical in developing effective mosquito control strategies, especially when an arboviral disease outbreak occurs. This study investigated the phenotypic and genotypic resistance of Hawaiian Ae. albopictus and Ae. aegypti to permethrin, one of the commonly used pyrethroids. Genomic sequences of 93 Ae. albopictus samples from four Hawaiian Islands (Kaua‘i, O‘ahu, Maui, and the Island of Hawai‘i) were screened for non-synonymous mutations in the voltage-gated sodium channel (VGSC) gene (chromosome 3:…
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Taxonomy
TopicsMosquito-borne diseases and control · Malaria Research and Control · Insect Pest Control Strategies
