# Tracheostomy in Flap‐Based Head and Neck Cancer Surgery: A Meta‐Analysis of Indications and Adverse Outcomes

**Authors:** Raisa Chowdhury, Khanh Linh Tran, Naser Karimi, Jhorrit Kahlon, Cornelius Kürten, Sena Turkdogan, Eitan Prisman

PMC · DOI: 10.1002/hed.70102 · 2025-11-21

## TL;DR

This study reviews when and why tracheostomies are used in head and neck cancer surgery and finds factors that predict their use and complications.

## Contribution

A meta-analysis quantifying tracheostomy rates and identifying predictors and complications in flap-based head and neck cancer surgery.

## Key findings

- The pooled tracheostomy rate was 54.6% across 27,029 patients.
- Advanced tumor stage, oropharyngeal site, and prior radiotherapy predicted tracheostomy use.
- The overall complication rate was 16.3%, with airway issues at 2.6%.

## Abstract

Tracheostomy is frequently performed during flap‐based reconstruction for head and neck cancer, but predictive factors and complications are not well established.

A systematic review and meta‐analysis was conducted per PRISMA guidelines. Studies of adult patients undergoing free or pedicled flap reconstruction were included. Pooled tracheostomy rates, predictors, and complications were analyzed using random‐effects models. Heterogeneity was assessed with the I2 statistic.

Twenty‐six studies (27 029 patients) were included. The pooled tracheostomy rate was 54.6%, decreasing to 42.4% when routine tracheostomy studies were excluded. Advanced tumor stage, oropharyngeal site, bilateral neck dissection, prior radiotherapy, and smoking predicted tracheostomy. Flap type was not significantly associated. The overall complication rate was 16.3%, including airway issues (2.6%). No significant change in tracheostomy rates was observed over 30 years.

Tracheostomy use is influenced by tumor, surgical, and patient factors. Selective tracheostomy and validated risk tools may improve outcomes. Further prospective studies are needed.

## Linked entities

- **Diseases:** head and neck cancer (MONDO:0005627)

## Full-text entities

- **Diseases:** tumor (MESH:D009369), Flap (MESH:D000070600), Head and Neck Cancer (MESH:D006258)
- **Chemicals:** Flap (MESH:C099563)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12797017/full.md

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Source: https://tomesphere.com/paper/PMC12797017