# Partial Laryngectomy for Thyroid Cancer: A Single Institution Case Series With Operative Techniques

**Authors:** Ella E. Hawes, Victoria E. Banuchi, Anastasios Maniakas, Jennifer R. Wang, Paul H. Graham, Julia D. Diersing, Naifa L. Busaidy, Maria E. Cabanillas, Ramona Dadu, Sarah Hamidi, Priyanka Iyer, Steven G. Waguespack, Salmaan Ahmed, Sahar Alizada, Alexandra Belcastro, Ranim Alsharif, Mimi I. Hu, Mark E. Zafereo

PMC · DOI: 10.1002/hed.28246 · 2025-08-01

## TL;DR

This paper presents a case series showing that partial laryngectomy can be a safe and effective treatment for thyroid cancer with limited laryngeal involvement.

## Contribution

The study introduces partial laryngectomy as a viable surgical option for thyroid cancer with laryngeal involvement, supported by positive outcomes in five patients.

## Key findings

- All patients had complete surgical resection without complications or postoperative speech or swallowing deficits.
- Only one patient experienced a laryngeal recurrence after a 26-month follow-up.
- Partial laryngectomy avoided the need for tracheostomy or feeding tubes in all patients.

## Abstract

Partial laryngectomy has been well described as a management option for T1–3 laryngeal squamous cell cancers. However, there are a few case reports of partial laryngeal surgery for locally advanced thyroid carcinoma.

This is a case series of five patients with thyroid carcinoma (one primary and four recurrent) with laryngeal involvement who underwent partial laryngectomy.

All patients had complete surgical resection without perioperative complications or postoperative speech or swallowing deficits, and none required a feeding tube or tracheostomy tube. No patients had postoperative radiation therapy or started systemic therapy within 2 years of surgery, while two patients had postoperative radioactive iodine. With a mean 26‐month follow‐up, only one patient had recurrence involving the larynx (cricoid cartilage recurrence at 26 months).

Partial laryngectomy should be considered for patients with thyroid cancer with limited laryngeal involvement.

## Linked entities

- **Diseases:** thyroid cancer (MONDO:0002108)

## Full-text entities

- **Diseases:** or swallowing deficits (MESH:D003680), Thyroid Cancer (MESH:D013964), T1-3 laryngeal squamous cell cancers (MESH:D018307)
- **Chemicals:** radioactive iodine (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12796987/full.md

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Source: https://tomesphere.com/paper/PMC12796987