# Selective embolization of a renal angiomyolipoma using n-butyl-2-cyanoacrylate‒lipiodol‒iopamidol mixture under microballoon occlusion resulting in tumor reduction and preservation of normal renal blood flow: A case report

**Authors:** Ryuta Okuhira, Nobuyuki Higashino, Tetsuo Sonomura, Maria Kojima, Akira Ikoma, Hiroki Minamiguchi

PMC · DOI: 10.1016/j.radcr.2025.11.070 · Radiology Case Reports · 2025-12-22

## TL;DR

A woman with a large kidney tumor underwent embolization using a special mixture to reduce the tumor while preserving normal kidney function.

## Contribution

A novel embolization mixture and technique was used to selectively treat a renal angiomyolipoma while preserving normal renal blood flow.

## Key findings

- The tumor's maximum diameter decreased from 56 mm to 39 mm after embolization.
- Embolization successfully occluded tumor feeding arteries while preserving normal kidney blood flow.
- Computed tomography confirmed long-term occlusion of embolized branches and maintained normal renal function.

## Abstract

A renal angiomyolipoma associated with sporadic lymphangioleiomyomatosis was found in the left kidney of a 30-year-old woman. The tumor had a maximum diameter of 56 mm, and there was a 5 mm diameter aneurysm within the tumor. Embolization using n-butyl-2-cyanoacrylate (NBCA)‒Lipiodol‒iopamidol mixtures was planned to prevent the tumor from rupturing. Under microballoon occlusion, NBCA:Lipiodol:iopamidol (1:4:1) mixture was injected into the peripheral part of the tumor and NBCA:Lipiodol:iopamidol (2:3:1) mixture was injected into the proximal part. Embolization completely occluded the feeding arteries of the tumor, and normal renal blood flow was preserved. Computed tomography performed 15 weeks after embolization showed that the embolized branches were completely occluded and normal renal blood flow was maintained. The maximum diameter of the tumor had decreased to 39 mm.

## Linked entities

- **Chemicals:** n-butyl-2-cyanoacrylate (PubChem CID 23087), iopamidol (PubChem CID 3734)
- **Diseases:** lymphangioleiomyomatosis (MONDO:0006277), angiomyolipoma (MONDO:0002603)
- **Species:** Homo sapiens (taxon 9606)

## Full-text entities

- **Diseases:** aneurysm (MESH:D000783), tumor (MESH:D009369), lymphangioleiomyomatosis (MESH:D018192), renal angiomyolipoma (MESH:D018207)
- **Chemicals:** iopamidol (MESH:D007479), NBCA (MESH:D004659), Lipiodol (MESH:D004998)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

13 references — full list in the complete paper: https://tomesphere.com/paper/PMC12796526/full.md

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Source: https://tomesphere.com/paper/PMC12796526