# RADS ALPHABET: news and tips for young and general radiologists

**Authors:** Roberto Cannella, Carolina Lanza, Giuseppe Pellegrino, Domenico Albano, Alessandra Bruno, Giuditta Chiti, Caterina Giannitto, Elisabetta Giannotti, Cristiano Michele Girlando, Francesca Grassi, Carmelo Messina, Rebecca Mura, Giuseppe Petralia, Arnaldo Stanzione, Federica Vernuccio, Fabio Zugni, Antonio Barile, Nicoletta Gandolfo, Gianpaolo Carrafiello, Serena Carriero

PMC · DOI: 10.1186/s13244-025-02154-8 · Insights into Imaging · 2026-01-12

## TL;DR

This paper provides a comprehensive guide to RADS for young and general radiologists to improve communication with clinicians and standardize medical reports.

## Contribution

An updated review of RADS frameworks with practical tips for their clinical implementation.

## Key findings

- RADS adoption is lower among non-academic and young radiologists.
- The paper outlines major RADS like BI-RADS and Lung-RADS with their imaging criteria.
- Implementation challenges can be addressed through education and standardization.

## Abstract

Reporting and Data Systems (RADS) aim at standardizing imaging acquisition, interpretation, lexicon, and reporting standards in specific patient populations, facilitating the communication between radiologists and clinicians. While the adoption of RADS has been supported by several studies and guidelines, with some of them endorsed by the American College of Radiology, the clinical adoption of the RADS algorithm remains heterogeneous among general practice radiologists worldwide, being lower in non-academic and young radiologists. This article aims to provide an updated review, aimed at young and general radiologists, of the RADS alphabet, discussing the main applications and imaging criteria with tips for their correct use in clinical practice. The following RADS will be discussed: BI-RADS, Bone-RADS, C-RADS, CAD-RADS, LI-RADS, Lung-RADS, MET-RADS-P, MY-RADS, NI-RADS, Node-RADS, O-RADS, ONCO-RADS, PI-RADS, ST-RADS, TI-RADS, and VI-RADS.

A comprehensive guide aimed at young and general radiologists featuring all of the major RADS with the objective to foster their implementation in clinical practice, which could be beneficial in a further standardization of the medical reports and in the communication between radiologists and clinicians.

RADS are outlined to enhance communication efficacy between radiologists and clinicians.Updated overview of RADS frameworks, detailing applications, imaging criteria, and advancements.RADS’ implementation remains a challenge, but can be addressed.

RADS are outlined to enhance communication efficacy between radiologists and clinicians.

Updated overview of RADS frameworks, detailing applications, imaging criteria, and advancements.

RADS’ implementation remains a challenge, but can be addressed.

## Full-text entities

- **Genes:** AZIN2 (antizyme inhibitor 2) [NCBI Gene 113451] {aka ADC, AZIB1, ODC-p, ODC1L, ODCp}, RAC1 (Rac family small GTPase 1) [NCBI Gene 5879] {aka MIG5, MRD48, Rac-1, TC-25, p21-Rac1}, AKT1 (AKT serine/threonine kinase 1) [NCBI Gene 207] {aka AKT, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA}
- **Diseases:** C2b lesion (MESH:D009059), non-ossifying fibroma (MESH:D018214), coronary stenosis (MESH:D023921), prostate (MESH:D011472), BI-RADS (MESH:D061325), pheochromocytoma syndromes (MESH:D010673), hereditary paraganglioma (MESH:D009386), Li-Fraumeni syndrome (MESH:D016864), benign prostatic hyperplasia (MESH:D011470), Thyroid (MESH:D013966), CAD (MESH:D003324), granulomatous chronic inflammation (MESH:D007249), constitutional mismatch repair deficiency syndrome (MESH:C536928), polyp (MESH:D011127), cystic (MESH:D018297), fracture (MESH:D050723), adnexal lesion (MESH:D000291), pulmonary (MESH:D008171), breast cancer (MESH:D001943), angio- or myolipomas (MESH:D007715), ST-RADS III lesions (MESH:D034721), ovarian and adnexal lesions (MESH:D010049), bone lesions (MESH:D001847), colonic diverticula (MESH:D004241), metastases (MESH:D009362), Node- (MESH:D012804), Prostate Cancer (MESH:D011471), Musculoskeletal soft tissue tumors (MESH:D012983), muscle (MESH:D019042), plasmacytoma (MESH:D010954), bony lesions (MESH:D000070896), calcifications (MESH:D002114), skeletal disease (MESH:D004194), NI (MESH:C564320), Trivasal coronary disease (MESH:D003327), calcium (MESH:D002128), BONE-RADS (MESH:D010001), hereditary retinoblastoma (MESH:D012175), lymph node malignancy (MESH:D000072717), tenosynovial giant cell tumor (MESH:D000070779), Liver Diseases (MESH:D008107), soft (MESH:C562950), fibromatosis (MESH:D005350), infectious (MESH:D003141), cirrhosis (MESH:D005355), hepatitis C (MESH:D019698), ovarian cancer (MESH:D010051), cyst (MESH:D003560), HCC (MESH:D006528), Tumor (MESH:D009369), invasive disease (MESH:D009361), LUNG-RADS (MESH:D008175), -RADS IV (MESH:D006011), NI-RADS (MESH:C564543), osteolysis (MESH:D010014), lipomatous tumor (MESH:D008080), dermoid cysts (MESH:D003884), adenocarcinoma (MESH:D000230), Head and Neck (MESH:D006258), bladder cancer (MESH:D001749)
- **Chemicals:** pomalidomide (MESH:C467566), Gadoxetate disodium (MESH:C073590), CEM (-), dexamethasone (MESH:D003907), Calcium (MESH:D002118), FDG (MESH:D019788), Daratumumab (MESH:C556306)
- **Species:** Homo sapiens (human, species) [taxon 9606], Human papillomavirus (species) [taxon 10566]
- **Cell lines:** CEM — Rattus norvegicus (Rat), Transformed cell line (CVCL_5U39)

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12796044/full.md

## Figures

13 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12796044/full.md

## References

12 references — full list in the complete paper: https://tomesphere.com/paper/PMC12796044/full.md

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Source: https://tomesphere.com/paper/PMC12796044