# Multifocal necrotising scleritis post-MIVS in oligoarticular JIA : exploring plausible deniability

## TL;DR

A 10-year-old boy with juvenile arthritis developed rare eye tissue death after surgery, which was managed with a combination of medical and surgical treatments.

## Contribution

First reported case of pediatric SINS following MIVS in a patient with oligoarticular JIA.

## Key findings

- Scleral necrosis localized to temporal sclerotomy sites with no infectious signs.
- Scleral melt stabilized after suture removal and surgical grafting.
- No recurrence observed over 12 months of follow-up.

## Abstract

To report and discuss the clinical features and management strategies for paediatric surgically induced necrotizing scleritis (SINS) following microincision vitrectomy surgery (MIVS), in a patient with underlying seronegative oligoarticular juvenile idiopathic arthritis (JIA).

Case report and review of literature.

A 10-year-old boy presented with multifocal areas of painless scleral necrosis following three-port 25-gauge pars plana vitrectomy. The area of scleral necrosis remained localized to the temporal sclerotomy sites, which were closed with 6 − 0 polyglactin sutures. There were no associated clinical signs of suppuration or discharge suggestive of an infectious etiology; the smear from the base of the scleral necrosis showed no microbial growth. Scleral melt remained progressive despite immunosuppressive therapy with intravenous methylprednisolone and cyclophosphamide. Systemically, the patient reported a recent onset of multiple joint pains without any visible joint swelling. The blood investigation returned negative for rheumatoid factor, ANA, and ANCA antibodies. Non-specific inflammatory markers (CRP) were significantly raised. The scleral necrosis stabilized following removal of the polyglactin suture. Scleral patch graft with conjunctivo-tenon flap helped to preserve the globe integrity. No recurrence or further necrosis was observed over twelve months of follow-up.

This is the first report on the clinical presentation of paediatric SINS associated with JIA following MIVS. Prior surgeries, underlying autoimmunity and use of polyglactin suture could have precipitated SINS which was recalcitrant to conventional immunosuppressants. A combined medical and surgical approach was helpful to achieve disease remission.