# The constrained disorder principle emphasizes the importance of variability boundaries for systems to function effectively

**Authors:** Yaron Ilan

PMC · DOI: 10.25122/jml-2025-0063 · Journal of Medicine and Life · 2025-11-01

## TL;DR

The paper introduces the Constrained Disorder Principle, which explains how systems function effectively by maintaining disorder within dynamic boundaries.

## Contribution

The novelty lies in formulating the principle as an equation (B = F) and applying it to understand and enhance system functionality.

## Key findings

- The dynamic borders (B) determine a system's function (F) and efficiency.
- Exceeding disorder limits reduces system performance, while insufficient disorder can also be harmful.
- The principle is applied to develop a second-generation AI system incorporating noise.

## Abstract

The Constrained Disorder Principle (CDP) defines systems by their inherent disorder, which is bounded by dynamic borders. This principle determines a system's functionality and efficiency based on its continuously changing boundaries. In this paper, we present the formulation of the principle using the equation B = F, where B represents the dynamic borders, and F denotes the system’s function. This equation suggests that the dynamic borders shape a system’s existence, functionality, and efficiency. However, these borders impose a limit beyond which the system cannot further enhance its performance. When disorder surpasses established limits, the system's efficiency begins to decline. Conversely, insufficient disorder may also be harmful in certain situations. The paper examines the causal relationship between disorder and function, illustrating how the equation reflects the system's adaptability, efficiency, learning capabilities, memory, energy consumption, aging, and eventual termination. We also discuss how this formula can be applied to correct malfunctions and enhance system functions. Furthermore, we introduce a second-generation artificial intelligence system based on the CDP formula that incorporates noise. In summary, the B = F equation provides a valuable framework for understanding complex systems and lays the groundwork for models designed to enhance system performance.

## Full-text entities

- **Genes:** GH1 (growth hormone 1) [NCBI Gene 2688] {aka GH, GH-N, GHB5, GHN, IGHD1A, IGHD1B}
- **Diseases:** cardiovascular disease (MESH:D002318), cancer (MESH:D009369), diabetes (MESH:D003920), death (MESH:D003643), hypertension (MESH:D006973), inflammation (MESH:D007249), CDP (MESH:D009358), genetic disorders (MESH:D030342), multiple sclerosis (MESH:D009103), heart disease (MESH:D006331), chronic pain (MESH:D059350), neurological diseases (MESH:D020271), congestive heart failure (MESH:D006333)
- **Chemicals:** CDP (-), auxin (MESH:D007210)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

100 references — full list in the complete paper: https://tomesphere.com/paper/PMC12794110/full.md

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Source: https://tomesphere.com/paper/PMC12794110