# Galaxy single-cell & spatial omics community update: Navigating new frontiers in 2025

## TL;DR

The Galaxy SPOC platform offers a unified, scalable solution for single-cell and spatial omics research with extensive tools and training resources.

## Contribution

Galaxy SPOC introduces a comprehensive, community-driven platform integrating leading tools for single-cell and spatial omics.

## Key findings

- Galaxy SPOC includes over 175 tools and 120 training resources for single-cell and spatial omics.
- The platform integrates leading tools like Scanpy, Seurat v5, and SpaceXR for scalable analyses.
- SPOC supports global collaboration and promotes FAIR principles in omics research.

## Abstract

Single-cell omics, named Method of the Year three times, have revolutionized biological research by enabling the high-resolution exploration of cellular heterogeneity and molecular processes. Initially centered on transcriptomics, this rapidly evolving field now ranges from multiomics to spatial analysis, with expanding customization options. The ubiquity of such analyses and the lack of a unified pipeline necessitate the development of scalable, flexible, and integrated tools and workflows. The Galaxy platform has responded to these technological advancements, extending its repertoire of freely accessible tools and workflows, backed by expert-reviewed and user-informed training resources to empower researchers to perform and interpret their own analyses. With more than 175 tools, 120 training resources, and 300,000 jobs running at the time of writing, this process has culminated in the development of Galaxy single-cell and spatial omics community (SPOC), designed to promote global collaboration in advancing usable, reproducible, accessible, and sustainable single-cell and spatial omics research.

The Galaxy single-cell and spatial omics community (SPOC) brings together over 175 tools, 120+ training resources, and a global user community in a unified FAIR platform. By integrating leading suites such as Scanpy, Seurat v5, SnapATAC2, muon, and SpaceXR, SPOC enables scalable and reproducible single-cell and spatial omics analyses. This community-driven initiative delivers adaptable workflows, sustained tool maintenance, and embedded best practices across the entire SPO data life cycle.