# Rosy Cells with a Rocky Core: Low-Grade Oncocytic Tumor with Osseous Metaplasia

**Authors:** Joseph Stenberg, Justin Tse, Emily Volpicelli

PMC · DOI: 10.15586/jkc.v13i1.439 · Journal of Kidney Cancer and VHL · 2026-01-06

## TL;DR

A rare kidney tumor with bone-like features is reported, adding to a small number of known cases.

## Contribution

This is the third documented case of low-grade oncocytic tumor with osseous metaplasia in the English literature.

## Key findings

- A 52-year-old female was diagnosed with a low-grade oncocytic tumor with osseous metaplasia.
- Such tumors are rare and typically have a favorable prognosis.

## Abstract

Osseous metaplasia is rarely reported in renal neoplasms and is predominantly associated with a favorable prognosis. Low-grade oncocytic tumor (LOT) represents a novel diagnostic classification of renal neoplasms that exhibit overlapping features of oncocytomas and chromophobe renal cell carcinoma. To the best of our knowledge, there are two definitive cases of low-grade oncocytic tumors with osseous metaplasia in the English literature. We present the third case of a 52-year-old female diagnosed with a low-grade oncocytic tumor exhibiting osseous metaplasia.

## Linked entities

- **Diseases:** chromophobe renal cell carcinoma (MONDO:0017885)

## Full-text entities

- **Diseases:** Oncocytic Tumor (MESH:C535584), renal neoplasms (MESH:D007680), Osseous Metaplasia (MESH:D008679), renal cell carcinoma (MESH:D002292), LOT (MESH:D008228), oncocytomas (MESH:D018249)

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12789880/full.md

## References

18 references — full list in the complete paper: https://tomesphere.com/paper/PMC12789880/full.md

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Source: https://tomesphere.com/paper/PMC12789880