# BICORN (Bilateral Iatrogenic Coronary Obstruction Risk Nullification) Procedure for Transcatheter Aortic Valve-in-Valve Replacement

**Authors:** Tariq Ahmad, Vernon Mascarenhas, Terry Bauch, Tyler Wallen, Russell Allan Carter

PMC · DOI: 10.1016/j.jaccas.2025.105145 · JACC Case Reports · 2025-09-10

## TL;DR

The BICORN procedure is a new technique to reduce coronary obstruction risk during valve-in-valve replacement in high-risk patients.

## Contribution

Introduces the BICORN method for translocating leaflets to safely deploy a new valve in transcatheter aortic valve replacement.

## Key findings

- BICORN involves translocating degenerated valve leaflets to prevent coronary obstruction.
- The procedure uses specific wires and balloons to safely advance and deploy the new valve.
- BICORN is proposed for patients with extreme surgical risk undergoing valve-in-valve replacement.

## Abstract

We describe a bilateral coronary leaflet modification technique that involves translocation of degenerated transcatheter valve leaflets before placement of valve-in-valve, named Bilateral Iatrogenic Coronary Obstruction Risk Nullification (BICORN).

Key steps include the following: 1) Electrified 0.014-in ASTATO wires were traversed through the base of the right and left coronary leaflets of preexisting CoreValve, which were then swapped with 0.035-in wires; 2) Using peripheral balloons, leaflet traversal points were appropriately dilated; 3) A 26-mm Sapien valve was then advanced over the wire through the left coronary leaflet to the ascending aorta in a deployment-ready state; and 4) Right coronary leaflet was then translocated with 18-mm True balloon followed by deployment of the Sapien valve lined up to sixth node of the CoreValve.

Translocation of preexisting valve leaflets is an uncontrolled step and can potentially lead to distal embolization and or severe aortic valve insufficiency.

BICORN can be considered as an option for transcatheter aortic valve in transcatheter aortic valve replacement in patients with extreme surgical risk.

## Full-text entities

- **Diseases:** POTENTIAL (MESH:C537245), aortic valve insufficiency (MESH:D001022), embolization (MESH:D004617), Coronary Obstruction (MESH:D000088442)
- **Chemicals:** BICORN (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

4 references — full list in the complete paper: https://tomesphere.com/paper/PMC12789795/full.md

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Source: https://tomesphere.com/paper/PMC12789795