# Transbaffle, Endocardial Systemic Right Ventricle Cardiac Resynchronization Therapy in D-Transposition of the Great Arteries

**Authors:** Nathan R. Smith, Dhaval R. Parekh, Enrique Garcia-Sayan, Kishan Dwarakanath, Wilson W. Lam

PMC · DOI: 10.1016/j.jaccas.2025.104936 · JACC Case Reports · 2025-08-06

## TL;DR

This paper describes a successful cardiac resynchronization therapy approach for a patient with d-transposition of the great arteries using an endocardial lead when traditional methods were not feasible.

## Contribution

The study demonstrates the effectiveness of transbaffle endocardial systemic right ventricle pacing as an alternative to coronary sinus lead implantation in complex cardiac anatomy.

## Key findings

- Endocardial systemic right ventricle pacing achieved QRS morphology similar to native conduction.
- The VersaCross system enabled successful transbaffle lead placement in a patient with d-transposition of the great arteries.
- The patient showed clinical improvement following the alternative pacing method.

## Abstract

Systemic right ventricular (SRV) cardiomyopathy commonly complicates d-transposition of the great arteries with previous atrial switch repair. Cardiac resynchronization therapy (CRT) is an effective therapy but may be difficult to achieve conventionally via coronary sinus (CS) lead implantation.

A 58-year-old man with a history of d-transposition of the great arteries and prior Mustard procedure presented with progressive dyspnea and QRS duration >200 milliseconds. No suitable CS branch was identified; therefore, we delivered CRT with endocardial SRV lead implantation via a VersaCross radiofrequency wire system. The patient experienced a QRS morphology similar to native conduction and an improvement in his symptoms and cardiac indices.

Systemic endocardial pacing has previously been demonstrated to be safe and effective in patients with normal cardiac anatomy.

Endocardial SRV leads for CRT are effective alternatives to CS lead. The VersaCross system is effective in delivering a transbaffle, SRV lead.

## Full-text entities

- **Diseases:** right ventricular (SRV) cardiomyopathy (MESH:C566255), D-Transposition of the Great Arteries (MESH:D014188), dyspnea (MESH:D004417)
- **Chemicals:** SRV lead (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12789758/full.md

## References

14 references — full list in the complete paper: https://tomesphere.com/paper/PMC12789758/full.md

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Source: https://tomesphere.com/paper/PMC12789758