# First-in-Human Experience With Septal Occluder for Dehiscence of Anterior Mitral Valve Leaflet Patch: From Surgical to Percutaneous Closure

## TL;DR

This paper presents the first case of using a septal occluder to treat a failed surgical repair of a heart valve after an infection.

## Contribution

The first reported use of a septal occluder for post-surgical dehiscence of an anterior mitral valve leaflet patch.

## Key findings

- Percutaneous closure with a septal occluder successfully abolished severe mitral regurgitation.
- The Gore Cardioform septal occluder was effective in treating a postsurgical complication from infective endocarditis.
- Device selection should be tailored to individual patient cases.

## Abstract

Mitral regurgitation secondary to infective endocarditis is often due to structural damage to the leaflets or apparatus, and the condition warrants surgical treatment. If surgery fails, percutaneous repair may be a viable option.

We describe a case of anterior mitral valve leaflet perforation after infective endocarditis, initially treated by surgical patch repair, with subsequent dehiscence leading to recurrence of severe mitral regurgitation. After percutaneous closure with a septal occluder device, regurgitation was abolished.

To our knowledge, this is the first case to demonstrate use of the Gore Cardioform septal occluder to treat postsurgical dehiscence of anterior mitral valve leaflet patch. Device selection needs to be decided on a case-by-case basis.

Percutaneous treatment of post–infective endocarditis anterior mitral valve leaflet perforation is feasible, even after failed surgical repair.