# Antimicrobial effect of plantago major extract against streptococcus mutans in dental caries formation

## TL;DR

This study shows that Plantago major extract can inhibit Streptococcus mutans, a bacteria linked to tooth decay, suggesting it could be a natural alternative to traditional treatments.

## Contribution

The study demonstrates the antimicrobial potential of Plantago major extract against Streptococcus mutans for dental caries control.

## Key findings

- Plantago major extract produced inhibition zones with a mean diameter of 9.95 mm against Streptococcus mutans.
- The extract's antimicrobial effect was statistically significant (p < 0.05) compared to chlorhexidine.
- The findings suggest Plantago major could be a natural therapeutic agent with fewer side effects for caries control.

## Abstract

This study evaluated the efficacy of Plantago major extract against Streptococcus mutans, a bacterium associated with biofilm formation and the development of dental caries, in search of natural alternatives to conventional methods of caries control. An experimental design was conducted using bioautography and broth microdilution techniques to assess the antimicrobial activity of the extract, with chlorhexidine serving as the comparative substance. The results demonstrated that Plantago major consistently produced inhibition zones with a mean diameter of 9.95 ± 0.41 mm, although smaller than those observed for chlorhexidine (CHX 1%) and CHX 0.12%, which averaged 14.98 ± 0.22 mm. Statistical analysis confirmed the significance of the antimicrobial effect of the extract (p < 0.05), suggesting its potential as a natural therapeutic agent. In conclusion, Plantago major extract showed promise as an alternative strategy for controlling dental caries, presenting a lower risk of side effects. These findings encourage further investigation into phytotherapeutic approaches and support the advancement of clinical research aimed at improving oral health and addressing the growing challenge of antimicrobial resistance.