# Impact of Vulvodynia on the Quality of Life of Women: A Rapid Review

**Authors:** María Fernanda Callirgos Escajadillo, Marina Gómez de Quero Córdoba, Marta Garrigues-Ramón, Sagrario Gómez-Cantarino, Adolfo Romero-Arana, Elena Arroyo-Bello

PMC · DOI: 10.3390/jcm15010070 · Journal of Clinical Medicine · 2025-12-22

## TL;DR

Vulvodynia, a chronic pain condition, significantly reduces women's quality of life across physical, psychological, and social aspects.

## Contribution

This rapid review synthesizes current evidence on quality of life in vulvodynia, highlighting affected domains and assessment tools.

## Key findings

- Vulvodynia consistently reduces quality of life in physical, psychological, and social dimensions.
- Common issues include chronic pain, sexual dysfunction, anxiety, depression, and social withdrawal.
- Multidisciplinary interventions improve emotional and physical well-being but often fail to resolve sexual dysfunction.

## Abstract

Background: Vulvodynia is a chronic vulvar pain syndrome with multifactorial etiology and unclear pathophysiology. Despite its high prevalence, it remains underdiagnosed and under-researched, with significant repercussions for women’s physical, psychological, and social well-being. Objective: To synthesize the available scientific evidence on quality of life (QoL) in women diagnosed with vulvodynia, identifying the main affected domains and the assessment tools used in the literature. Methods: A rapid review was conducted following PRISMA 2020 and Cochrane Rapid Reviews guidelines. Searches were performed in PubMed, Web of Science, Scopus, CINAHL, Biblioteca Virtual en Salud, and CUIDEN without date or geographic restrictions. Studies including adult women diagnosed with vulvodynia and reporting QoL outcomes were eligible. Data was extracted and synthesized narratively, and methodological quality was assessed using the Mixed Methods Appraisal Tool (MMAT). Results: Twenty studies published between 2006 and 2025 met the inclusion criteria (13 quantitative and 7 qualitative). Vulvodynia was consistently associated with reduced QoL across physical, psychological, and social dimensions. The most frequently reported issues were chronic vulvar pain, sexual dysfunction, anxiety, depression, and social withdrawal. Tools such as SF-12, SF-36, WHOQOL-BREF, DLQI, Skindex-29, and SQLQ-F were commonly used, although heterogeneity among instruments limited comparability. Multidisciplinary interventions combining physiotherapy and psychological therapy showed improvements in emotional and physical well-being, though sexual dysfunction often persisted. Conclusions: Vulvodynia substantially impairs women’s quality of life, reflecting complex biopsychosocial interactions. The findings highlight the need for standardized QoL measures and gender-sensitive, multidisciplinary approaches to diagnosis, management, and research.

## Linked entities

- **Diseases:** vulvodynia (MONDO:0021722)

## Full-text entities

- **Diseases:** sexual dysfunction (MESH:D012735), Vulvodynia (MESH:D056650), depression (MESH:D003866), anxiety (MESH:D001007), vulvar pain (MESH:D014845)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

41 references — full list in the complete paper: https://tomesphere.com/paper/PMC12787231/full.md

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Source: https://tomesphere.com/paper/PMC12787231