# Phenotypic Analysis of Intentionally Created Monocular Visual Field Defects During Bilateral Randomized Visual Field Testing Using the Imo Vifa®

**Authors:** Yuiko Kawaguchi, Yuki Takagi, Takashi Kojima, Akeno Tamaoki, Tatsushi Kaga

PMC · DOI: 10.3390/jcm15010009 · Journal of Clinical Medicine · 2025-12-19

## TL;DR

The study examined how well people could simulate specific visual field defects using a device called imo Vifa® and found that the results varied based on participants' understanding and training.

## Contribution

This study evaluates the imo Vifa®'s ability to detect malingering by analyzing simulated monocular visual field defects in healthy individuals.

## Key findings

- Accurate simulation of intended visual field defects was challenging for participants.
- Orthoptists produced more accurate defect patterns compared to non-certified participants.
- Participants' understanding of the test influenced the resulting visual field patterns.

## Abstract

Background/Objectives: The imo Vifa® is reportedly useful for diagnosing functional visual field loss; however, its potential for detecting malingering is unclear. Here, we intentionally simulated monocular visual field defects under bilateral randomized visual field testing conditions using the imo Vifa® in healthy participants and compared their resulting defect phenotypes. Methods: Twenty participants (mean age, 37.3 ± 12.4 years; 12 orthoptists, 1 physician, and 7 administrative staff members) without ocular disease were enrolled. Four types of monocular visual field defects were simulated: right eye nasal hemianopia, left eye temporal hemianopia, right eye centripetal visual field constriction, and left eye central scotoma. Bilateral randomized visual field testing was performed using the AIZE-rapid mode with the 24-2 and 24plus(1) programs. Results: Accurate simulation of the intended defects was challenging. Orthoptists produced left homonymous hemianopia for right nasal hemianopia and left temporal hemianopia. Regarding right nasal hemianopia, many office workers generated patterns resembling right homonymous hemianopia-like, whereas for left temporal hemianopia, noncertified orthoptists produced patterns similar to those of left homonymous hemianopia-like. Considering the right centripetal constriction, all orthoptists produced the intended centripetal constriction, whereas non-orthoptists generated right homonymous hemianopia-like or patchy patterns. Orthoptists produced central scotomas or patchy patterns for the left central scotoma, whereas non-orthoptists generated left homonymous hemianopia-like patterns. Conclusions: Creating targeted monocular abnormalities during bilateral randomized visual field testing was challenging. Differences in the participants’ understanding of visual field testing influenced the resulting patterns. In future research, having participants create monocular visual field defects under occlusion conditions would be necessary.

## Full-text entities

- **Diseases:** central scotoma (MESH:D012607), visual field loss (MESH:D014786), constriction (MESH:D015877), homonymous hemianopia (MESH:D006423), ocular disease (MESH:D005128), Monocular Visual Field Defects (MESH:D001766)
- **Chemicals:** Imo (-)

## Full text

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## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12786814/full.md

## References

16 references — full list in the complete paper: https://tomesphere.com/paper/PMC12786814/full.md

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Source: https://tomesphere.com/paper/PMC12786814