# MistGo® Compared to Conventional Eye Drops: A Patient-Reported Evaluation of Comfort and User-Friendliness in Glaucoma Treatment

**Authors:** Astrid Dissing Sjö, Marie Louise Holm Møller, Rune Nørager, Nicolai Sjö, Miriam Kolko

PMC · DOI: 10.3390/jcm15010067 · Journal of Clinical Medicine · 2025-12-22

## TL;DR

A new mist-based eye drop device called MistGo® was found to be more comfortable and easier to use than traditional eye drops for glaucoma patients.

## Contribution

This study provides patient-reported evidence that MistGo® improves comfort and user-friendliness compared to conventional eye drop dispensers.

## Key findings

- MistGo® was rated significantly higher in comfort and user-friendliness compared to conventional eye drops.
- Participants were less likely to apply medication outside the eye with MistGo®.
- 20 out of 22 patients preferred MistGo® over traditional dispensers.

## Abstract

Background/Objectives: Poor adherence remains a key challenge in glaucoma management, often due to difficulties with accurate self-administration and discomfort associated with conventional eye drop bottles. MistGo® is a novel dispensing device that delivers precise micro-doses of medication as a fine mist, allowing dosing with a neutral head position. With its ergonomic design, eye rest, and dose release button, MistGo® aims to improve comfort and ease of use. This study compared the user-friendliness, comfort, and administration confidence of MistGo® versus conventional eye drop dispensers in patients using topical ocular hypotensive medications. Methods: Twenty-two patients with glaucoma or ocular hypertension who had used conventional eye drop dispensers for ≥3 months were enrolled. Participants used the MistGo® device for 14 days and subsequently rated comfort, user-friendliness, and administration confidence on 0–10 scales for both their conventional dispensers and the MistGo® device. Results: MistGo® was rated significantly higher than conventional eye drop dispensers in terms of comfort (p < 0.0001), caused less discomfort from excess fluid (p < 0.001), and was perceived as more user-friendly (p < 0.001). There was no significant difference in the perceived accuracy of administration (p = 0.5); however, participants reported a significantly lower likelihood of medication being applied outside the eye when using MistGo® (p < 0.001). Overall, 20 out of 22 patients preferred MistGo®. Conclusions: Patients with glaucoma or ocular hypertension preferred MistGo® over conventional eye drop dispensers as they found it more comfortable and user-friendly. These findings suggest that MistGo® has the potential to reduce barriers to adherence in glaucoma care. Further studies are warranted to evaluate its long-term efficacy and broader applicability.

## Linked entities

- **Diseases:** glaucoma (MONDO:0005041), ocular hypertension (MONDO:0006875)

## Full-text entities

- **Diseases:** ocular hypertension (MESH:D009798), Glaucoma (MESH:D005901), ocular hypotensive medications (MESH:D015814)
- **Chemicals:** MistGo (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

36 references — full list in the complete paper: https://tomesphere.com/paper/PMC12786802/full.md

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Source: https://tomesphere.com/paper/PMC12786802