# Unravelling the Mystery of Psoriasis Dermatitis (PsoDermatitis): A Practical Guide to Recognition and Management

## TL;DR

This paper explores how psoriasis and atopic dermatitis can coexist in the same person, challenging previous assumptions about these skin conditions.

## Contribution

The paper introduces the term 'PsoDermatitis' to describe the coexistence of psoriasis and atopic dermatitis and reviews their shared characteristics.

## Key findings

- Psoriasis and atopic dermatitis can coexist in the same individual, challenging the traditional view of their mutual exclusivity.
- The paper reviews the nomenclature, epidemiology, genetics, and clinical features of coexistent psoriasis and atopic dermatitis.

## Abstract

Historically, psoriasis (Pso) and atopic dermatitis (AD) were considered mutually exclusive diseases due to their activation of opposing immune pathways—Th17 in Pso and Th2 in AD. However, growing clinical evidence and systematic reviews have challenged this dichotomy, demonstrating that both conditions can coexist in the same individual. This paper aims to provide an overview of the nomenclature, epidemiology, genetics, pathogenesis, and clinical features of coexistent psoriasis and atopic dermatitis, whether drug-induced or not. These conditions are also collectively referred to as “PsoDermatitis”.