# Hot Topics in Implant-Based Breast Reconstruction

**Authors:** Thomas J. Sorenson, Carter J. Boyd, Nolan S. Karp

PMC · DOI: 10.3390/jcm15010263 · Journal of Clinical Medicine · 2025-12-29

## TL;DR

This review discusses the latest developments and challenges in implant-based breast reconstruction, focusing on techniques, materials, and safety concerns.

## Contribution

The paper identifies and summarizes eight current hot topics shaping the field of implant-based breast reconstruction.

## Key findings

- Prepectoral reconstruction is gaining popularity due to reduced pain and animation deformity.
- Nipple-sparing mastectomy improves aesthetics and enables functional recovery through NAC neurotization.
- Next-generation implants and biologic matrices are expanding reconstructive options but raise safety concerns.

## Abstract

Implant-based breast reconstruction (IBBR) remains the most common form of post-mastectomy reconstruction worldwide, offering patients a reliable and accessible option to restore breast contour. Advances in surgical technique, biomaterials, and implant technology have driven rapid evolution in the field, with the dual goals of improving aesthetic outcomes and minimizing patient morbidity. The prepectoral plane has been popularized due to the eliminated risk of animation deformity and reduced postoperative pain. Some concerns remain regarding mastectomy flap thickness and long-term oncologic and aesthetic outcomes. Concurrently, nipple-sparing mastectomy has improved aesthetic results and enabled surgeons to move beyond just restoring breast form and improve functional recovery as well, as demonstrated by surgical efforts aimed at restoring nipple–areolar complex (NAC) sensation. Adjunctive use of biologic matrices and synthetic meshes has broadened reconstructive options, while next-generation implants seek to further enhance outcomes. Balanced against these innovations are important oncologic and systemic safety concerns, including breast implant-related cancers and the ongoing debate over breast implant illness (BII). This review highlights eight current “hot topics” in implant-based breast reconstruction: (1) prepectoral reconstruction, (2) nipple-sparing mastectomy, (3) oncoplastic techniques, (4) nipple–areolar complex (NAC) neurotization, (5) biologic matrices and synthetic meshes, (6) next-generation implants, (7) optimizing aesthetic outcomes, and (8) implant-associated cancer and systemic concerns. Together, these areas define the current landscape of innovation, controversy, and future directions in implant-based reconstruction.

## Linked entities

- **Diseases:** breast implant illness (MONDO:0858974)

## Full-text entities

- **Diseases:** postoperative pain (MESH:D010149), cancer (MESH:D009369)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

100 references — full list in the complete paper: https://tomesphere.com/paper/PMC12786434/full.md

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Source: https://tomesphere.com/paper/PMC12786434