# Editorial: CRISPR-Based Genome Editing in Translational Research—2nd Edition

**Authors:** Jie Xu, Jifeng Zhang, Dongshan Yang

PMC · DOI: 10.3390/cells15010035 · Cells · 2025-12-24

## Full-text entities

- **Genes:** MLH1 (mutL homolog 1) [NCBI Gene 4292] {aka COCA2, FCC2, HNPCC, HNPCC2, LYNCH2, MLH-1}, ATP7B (ATPase copper transporting beta) [NCBI Gene 540] {aka PWD, WC1, WD, WND}, HTT (huntingtin) [NCBI Gene 3064] {aka HD, IT15, LOMARS}, adgrv1 (adhesion G protein-coupled receptor V1) [NCBI Gene 415105] {aka gpr98, mass1, vlgr1}
- **Diseases:** Huntington's disease (MESH:D006816), inherited disorder of copper metabolism (MESH:D020739), retinal dysfunction (MESH:D012164), injury to (MESH:D014947), retinal disorders (MESH:D012173), monogenic diseases (MESH:D004194), Cancer (MESH:D009369), Usher syndrome (MESH:D052245), Mitochondrial Diseases (MESH:D028361), Wilson disease (MESH:D006527), neuroblastoma (MESH:D009447)
- **Chemicals:** copper (MESH:D003300)
- **Species:** Homo sapiens (human, species) [taxon 9606], Macaca mulatta (rhesus macaque, species) [taxon 9544], Danio rerio (leopard danio, species) [taxon 7955]
- **Mutations:** 3243A>G

## Full text

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## References

48 references — full list in the complete paper: https://tomesphere.com/paper/PMC12785915/full.md

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Source: https://tomesphere.com/paper/PMC12785915