# Special Issue “The Role of Natural Products in Drug Discovery”

**Authors:** Luciana Scotti, Marcus Tullius Scotti

PMC · DOI: 10.3390/ijms27010246 · International Journal of Molecular Sciences · 2025-12-25

## Full-text entities

- **Genes:** MITF (melanocyte inducing transcription factor) [NCBI Gene 4286] {aka CMM8, COMMAD, MI, MITF-A, WS2, WS2A}, AR (androgen receptor) [NCBI Gene 367] {aka AIS, AR8, DHTR, HPCX3, HUMARA, HYSP1}
- **Diseases:** hyperpigmentation (MESH:D017495), pain (MESH:D010146), prostate cancer (MESH:D011471), injury to (MESH:D014947), Inflammatory (MESH:D007249)
- **Chemicals:** melanin (MESH:D008543), Cinnamic Acid (MESH:C029010), tetracyclines (MESH:D013754), eriocitrin (MESH:C114706), osthole (MESH:C046627), Lipid (MESH:D008055), capsaicin (MESH:D002211), 4-HC (MESH:C011272), berberine (MESH:D001599), formalin (MESH:D005557), Flavonoid (MESH:D005419), Alkaloids (MESH:D000470), acetic acid (MESH:D019342), glutamate (MESH:D018698), nitidine (MESH:C013615), penicillin (MESH:D010406), PGG (MESH:C435084), doxorubicin (MESH:D004317), 4-Hydroxycoumarin (MESH:C068805), ethyl-4-methoxycinnamate (MESH:C531364), Eriomin (-), rotundine (MESH:C014215), Protoberberine (MESH:C009090), resorcinol (MESH:C031389), paclitaxel (MESH:D017239)
- **Species:** Streptomyces (genus) [taxon 1883], Citrus x limon (lemon, species) [taxon 2708], Crocus alatavicus (species) [taxon 481013], Aspalathus linearis (rooibos, species) [taxon 155124], Homo sapiens (human, species) [taxon 9606], Rattus norvegicus (brown rat, species) [taxon 10116]
- **Cell lines:** B16F10 — Mus musculus (Mouse), Mouse melanoma, Cancer cell line (CVCL_0159)

## Full text

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## References

7 references — full list in the complete paper: https://tomesphere.com/paper/PMC12785763/full.md

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Source: https://tomesphere.com/paper/PMC12785763