# Prenatal Detection of a Right Atrial Echogenic Mass: A Case Report of Hypertrophic Crista Terminalis

**Authors:** Mariangela Pati, Maria Paola Bonasoni, Andrea Musarò, Benedetta Petrachi, Francesco Di Dio, Elena Chesi, Francesco Leo, Giulia Barbato, Sonia Ricò, Giancarlo Gargano, Khush Shah, Lorenzo Aguzzoli

PMC · DOI: 10.3390/diagnostics16010017 · Diagnostics · 2025-12-20

## TL;DR

This case report describes a prenatal detection of a right atrial mass that was later identified as a normal anatomical variant called hypertrophic crista terminalis.

## Contribution

The paper adds a rare prenatal case of hypertrophic crista terminalis to the literature, emphasizing its potential to mimic pathological masses.

## Key findings

- The fetal echogenic mass remained stable throughout gestation and showed no signs of pathology.
- Postnatal confirmation indicated the mass was a likely hypertrophic crista terminalis, not a tumor or thrombus.
- The case highlights the importance of considering anatomical variants in the differential diagnosis of intracardiac masses.

## Abstract

Background and Clinical Significance: The crista terminalis (CT) is a fibromuscular ridge located on the posterolateral wall of the right atrium, formed by the junction of the sinus venosus and the primitive right atrium. A hypertrophic or prominent CT (HCT) refers to a thickened or conspicuous configuration of this normal anatomical structure. In prenatal ultrasound (US) and/or echocardiographic assessments, HCT can mimic a right atrial mass, such as a tumor or a thrombus. Case Presentation: Herein, we describe a case of a fetal right atrial echogenic mass detected at 32 weeks, which remained stable through gestation and was confirmed postnatally as a likely HCT. No hemodynamic compromise, growth, or pathological sequelae were observed. Conclusions: Our case reinforces the importance of including atrial structural variants in the differential diagnosis of intracardiac masses, particularly when features favor stability and low risk. Serial imaging, avoidance of premature invasive measures, and careful counseling are key to appropriate management.

## Full-text entities

- **Diseases:** HCT (MESH:C000721290), thrombus (MESH:D013927), Hypertrophic Crista Terminalis (MESH:C565016), right atrial mass (MESH:C536030), hypertrophic (MESH:D002312), Echogenic Mass (MESH:D058535), intracardiac masses (MESH:C538262), tumor (MESH:D009369)

## Full text

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## Figures

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## References

25 references — full list in the complete paper: https://tomesphere.com/paper/PMC12785512/full.md

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Source: https://tomesphere.com/paper/PMC12785512