# Impact of Social Media on HPV Vaccine Knowledge and Attitudes Among Adolescents and Young Adults: A Systematic Literature Review

**Authors:** Blessing Oluwatofunmi Apata, Anagha Hemant Tupe, Oluwabusayomi Akeju, Kelly L. Wilson

PMC · DOI: 10.3390/healthcare14010073 · Healthcare · 2025-12-27

## TL;DR

This review explores how social media affects teenagers and young adults' knowledge and attitudes about the HPV vaccine, finding both positive and negative influences.

## Contribution

The study systematically reviews the impact of social media on HPV vaccine knowledge and attitudes, highlighting the role of misinformation and effective intervention strategies.

## Key findings

- Social media interventions can increase HPV vaccine knowledge and intentions among adolescents and young adults.
- Exposure to anti-vaccine content is linked to lower vaccination intentions, especially among those with low prior knowledge.
- Interactive and loss-framed social media content is more effective in promoting vaccination intentions.

## Abstract

Objective: Human Papillomavirus (HPV), a leading cause of sexually transmitted infections (STIs) and various cancers, including cervical cancer, remains prevalent in the US. Despite the HPV vaccine’s effectiveness in preventing persistent HPV infections, vaccination rates remain low. Given the significant role of social media in reaching younger populations, this systematic review examines its influence on adolescents’ and young adults (AYAs) awareness, knowledge, and attitudes toward HPV vaccination. Methods: Following the PRISMA guidelines, we conducted a comprehensive search across six electronic databases (ERIC, APA PsycInfo, Child Development & Adolescent Studies, CINAHL Ultimate, MEDLINE Ultimate, and PubMed) from 2011 to 2024. Empirical studies that examined the association between social media use and HPV were included. Data extraction captured the study’s purpose, design, population, outcome measures, and key results. Results: Seven studies satisfied the review’s inclusion criteria. Our findings reveal mixed effects of social media on AYAs’ knowledge and vaccination intentions. Some studies indicated positive associations between social media interventions and increased vaccination knowledge and intentions, while others found no significant impact. Additionally, exposure to anti-vaccine content was linked to lower vaccination intentions, especially among individuals with lower knowledge who were more vulnerable to misinformation. Interventions incorporating interactive content and loss-framed messaging were more effective in increasing vaccine intentions. Conclusions: This review underscores the potential of social media to influence AYAs knowledge and perceptions regarding HPV vaccination, while also highlighting the challenges posed by misinformation. Further research is needed to optimize social media interventions and combat misinformation to improve vaccination uptake.

## Linked entities

- **Diseases:** cervical cancer (MONDO:0002974)

## Full-text entities

- **Diseases:** HPV infections (MESH:D030361), cancers (MESH:D009369), cervical cancer (MESH:D002583), STIs (MESH:D012749)
- **Species:** Human papillomavirus (species) [taxon 10566]

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## References

55 references — full list in the complete paper: https://tomesphere.com/paper/PMC12785451/full.md

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Source: https://tomesphere.com/paper/PMC12785451