# Cardiovascular Prevention: Current Gaps and Future Directions

**Authors:** Hélder Dores, José Ferreira Santos, Victor Gil, Pedro de Araújo Gonçalves

PMC · DOI: 10.3390/diagnostics16010016 · Diagnostics · 2025-12-20

## TL;DR

This paper reviews current challenges in preventing cardiovascular disease and suggests future strategies like digital health and precision medicine.

## Contribution

The paper outlines a multi-level approach combining clinical, personalized, and policy strategies for better cardiovascular prevention.

## Key findings

- Current prevention strategies face challenges in lifestyle adherence and pharmacological management.
- Digital health and precision medicine are highlighted as promising future directions.
- A multi-level approach integrating clinical and policy strategies is needed to reduce CVD impact.

## Abstract

Cardiovascular Disease (CVD) remains the leading cause of morbidity and mortality worldwide. Despite significant advances in diagnosis and treatment, the global burden of CVD remains high, underscoring the crucial need for more effective and comprehensive prevention strategies. This narrative overview aims to critically evaluate the current pillars of cardiovascular prevention, identify the gaps in approaches and outline promising future directions. Challenges and barriers in lifestyle adherence and pharmacological management are addressed, while the increasing role of non-traditional and emerging risk factors is discussed. Future directions include maximizing the value of digital health to improve patient engagement and adherence, adopting precision medicine to refine risk stratification and implementing public health policies for population-level interventions. The optimization of cardiovascular prevention requires a multi-level approach that integrates clinical strategies with personalized solutions and environmental policies to ultimately reduce the global impact of CVD.

## Linked entities

- **Diseases:** Cardiovascular Disease (MONDO:0004995)

## Full-text entities

- **Diseases:** CVD (MESH:D002318)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12785342/full.md

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12785342/full.md

## References

94 references — full list in the complete paper: https://tomesphere.com/paper/PMC12785342/full.md

---
Source: https://tomesphere.com/paper/PMC12785342