# Comparing content within a culturally-adapted digital treatment for Hispanic patients with alcohol use disorder

**Authors:** Bryan Benitez, Tami Frankforter, Charla Nich, Manuel Paris, Brian D. Kiluk

PMC · DOI: 10.1038/s41746-025-02197-7 · NPJ Digital Medicine · 2025-12-08

## TL;DR

This study examines how a culturally adapted digital therapy for Hispanic individuals with alcohol use disorder affects treatment outcomes.

## Contribution

The study identifies specific therapy topics most strongly linked to reduced alcohol use in Hispanic patients.

## Key findings

- Content on coping with craving was most strongly linked to reduced alcohol use.
- Cognitive restructuring and problem-solving topics also showed significant associations.
- Participants found cognitive restructuring and decision-making content more favorable.

## Abstract

Hispanic people in the U.S. experience alcohol-related harms comparable to non-Hispanic White people. Hispanic people often face more challenges to accessing alcohol use disorder (AUD) treatment. Culturally-adapted digital therapeutics may improve treatment access. Using data from two clinical trials of a culturally-adapted digital cognitive behavioral therapy program for Spanish-speaking Hispanic people (CBT4CBT-S, n = 43), we identified which program topics were most strongly linked to outcomes (NCT03474588 registered on 3/15/2018 and NCT02043210 registered on 1/10/2014 at clinicaltrials.gov). Topics were not administered in a randomized order. Participants drank less alcohol after completing content about coping with craving (OR = 0.48), cognitive restructuring (OR = 0.73), and problem solving (OR = 0.79). Participants were slightly more favorable towards content about cognitive restructuring (b = 0.14) and decision making (b = 0.09). These findings can inform further development of culturally-adapted digital therapeutics for AUD, which may improve alcohol-related health outcomes for Hispanic people.

## Full-text entities

- **Diseases:** alcohol-related harms (MESH:D019973), AUD (MESH:D000437)
- **Chemicals:** alcohol (MESH:D000438)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

16 references — full list in the complete paper: https://tomesphere.com/paper/PMC12783792/full.md

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Source: https://tomesphere.com/paper/PMC12783792