# Antimicrobial resistance databases: opportunities and challenges for public health **Authors:** Chad M. Centner, Sabrina Di Gregorio, Silvia Argimón, Alice Brankin, Anna Dean, Daniel Marcano Zamora, Silvia Bertagnolio PMC · DOI: 10.1038/s44259-025-00169-1 · npj Antimicrobials and Resistance · 2026-01-08 ## TL;DR This paper reviews AMR databases and discusses how they can improve tracking and managing antimicrobial resistance in public health. ## Contribution The paper provides a comparative analysis of AMR databases and identifies challenges and opportunities for their use in public health. ## Key findings - AMR databases help identify resistance determinants from pathogen sequences. - Regularly updated databases enhance AMR surveillance and public health interventions. ## Abstract Antimicrobial resistance (AMR) databases enable the identification of AMR determinants from pathogen sequence data and the prediction of resistance profiles, enhancing AMR surveillance and informing a range of public health interventions. This review compares freely available and regularly updated AMR databases, explores their public health value and highlights key challenges to and opportunities for fully harnessing their potential. ## Full-text entities - **Genes:** blaNDM-1 [NCBI Gene 17373266], dihydrofolate reductase [NCBI Gene 15407953], Beta-Lactamase [NCBI Gene 18262323], extended-spectrum beta-lactamase [NCBI Gene 13982007] - **Diseases:** K. pneumoniae infections (MESH:D011014), drug-resistant tuberculosis (MESH:D018088), Antibiotic (MESH:D004761), AMR (MESH:D060467), Infection (MESH:D007239), AST (MESH:D013736), MTBc (MESH:D014376), TB (MESH:D014390) - **Chemicals:** penicillins (MESH:D010406), rifampicin (MESH:D012293), rifabutin (MESH:D017828), delamanid (MESH:C516022), carbapenem (MESH:D015780), bedaquiline (MESH:C493870), fluoroquinolone (MESH:D024841), ampicillin (MESH:D000667), beta-lactam (MESH:D047090), cephalosporin (MESH:D002511), trimethoprim (MESH:D014295), aminoglycoside (MESH:D000617), ISAba1 (-), linezolid (MESH:D000069349) - **Species:** Escherichia coli (E. coli, species) [taxon 562], Salmonella enterica subsp. enterica serovar Typhi (no rank) [taxon 90370], Klebsiella pneumoniae (species) [taxon 573], Mycobacterium tuberculosis (species) [taxon 1773], Enterococcus faecium (species) [taxon 1352], Homo sapiens (human, species) [taxon 9606], Pseudomonas aeruginosa (species) [taxon 287], Haemophilus influenzae (species) [taxon 727], Neisseria gonorrhoeae (species) [taxon 485], Streptococcus pneumoniae (species) [taxon 1313], Vibrio cholerae (species) [taxon 666], Acinetobacter baumannii (species) [taxon 470], Mycobacterium tuberculosis complex (species group) [taxon 77643], Staphylococcus aureus (species) [taxon 1280] ## Full text _Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12783659/full.md ## Figures 2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12783659/full.md ## References 44 references — full list in the complete paper: https://tomesphere.com/paper/PMC12783659/full.md --- Source: https://tomesphere.com/paper/PMC12783659