# Regenerative Approach With Autologous Fat Grafting and Stem Cells for the Treatment of Post‐Traumatic Anal Incontinence: A Case Report

**Authors:** Alexandre da Silva Nishimura, Giuliana Donoso Andrade Silva, Vitor Holmo Figueira, Eduardo Isaac Nishimoto, Pedro Luiz Nishimura Menardi, Igor Rincon Gonçalves Passaglia, Sabrina Thalita dos Reis

PMC · DOI: 10.1002/ccr3.71619 · Clinical Case Reports · 2026-01-08

## TL;DR

A regenerative therapy using fat grafts and stem cells may help treat anal incontinence caused by trauma.

## Contribution

The paper introduces a novel regenerative treatment combining autologous fat grafting and stem cells for post-traumatic anal incontinence.

## Key findings

- Autologous fat grafting enriched with mesenchymal stem cells is a promising therapy for post-traumatic anal incontinence.
- The treatment may restore continence and improve quality of life despite persistent sphincter defects.

## Abstract

Autologous fat grafting enriched with mesenchymal stem cells is a promising minimally invasive regenerative therapy for post‐traumatic anal incontinence. This approach may restore continence and quality of life, even when structural sphincter defects persist.

## Full-text entities

- **Diseases:** Anal Incontinence (MESH:D001005), sphincter defects (MESH:D009122)

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12783066/full.md

## References

19 references — full list in the complete paper: https://tomesphere.com/paper/PMC12783066/full.md

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Source: https://tomesphere.com/paper/PMC12783066