# No Alterations in ACL Injury Risk Factors in Preadolescent Elite Female Handball Players Following an Eight‐Week Targeted Training Intervention: A Randomised Controlled Trial

**Authors:** Niels J. Nedergaard, Jesper Bencke, Johanna Egholm, August L. Nielsen, Anke N. Karabanov, Jesper Lundbye-Jensen, Mette K. Zebis

PMC · DOI: 10.1155/tsm2/2570210 · Translational Sports Medicine · 2026-01-02

## TL;DR

An 8-week ACL injury prevention program did not significantly reduce injury risk factors in preadolescent female handball players.

## Contribution

This study evaluates the effectiveness of a targeted ACL injury prevention program in preadolescent athletes.

## Key findings

- No significant changes in semitendinosus preactivity or biomechanical risk factors were observed after the 8-week intervention.
- Retention effects at 8-week follow-up also showed no meaningful improvements.
- The program may require adjustments in volume, exercise selection, or duration to be effective.

## Abstract

Adolescent female handball players are at elevated risk of anterior cruciate ligament (ACL) injury. Early interventions during preadolescence seem crucial for improving motor strategies and potentially preventing injuries. This randomised controlled trial on preadolescent female handball players investigated the effects of an 8‐week ACL injury prevention program (ACL‐IPP) targeting modifiable neuromuscular and biomechanical risk factors and assessed retention effects 8 weeks post‐intervention. Thirty‐five elite preadolescent female handball players (11–13 years old) were randomised to the ACL‐IPP group (n = 18) or a control group that performed shoulder injury prevention exercises (n = 17), with supervised training conducted for 15 min twice weekly. Biomechanical and neuromuscular assessments of participants’ side‐cutting manoeuvres were performed at baseline, immediately after the 8‐week intervention (post‐intervention) and at an 8‐week follow‐up (16 weeks from baseline). The primary outcome was the between‐group change in m. semitendinosus EMG preactivity, measured during the 50 ms preceding initial contact of the side‐cutting manoeuvre at 8 weeks. There were no significant between‐group differences in changes in semitendinosus preactivity (p = 0.950), isometric hip external rotation strength, hip flexion, knee internal rotation at initial contact or peak knee abduction moments of the handball‐specific side‐cut manoeuvre. Similarly, no retention effects were observed after 16 weeks. These findings suggest that the implemented 8‐week ACL‐IPP was insufficient to elicit meaningful improvements in ACL injury risk factors in this population. Greater training volume, different exercise selection and/or extended intervention duration may be required to induce neuromuscular and biomechanical adaptations in preadolescent female handball players.

Trial Registration: ClinicalTrials.gov identifier: NCT05955599

## Full-text entities

- **Diseases:** shoulder injury (MESH:D000070599), ACL Injury (MESH:D000070598)

## Full text

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## Figures

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## References

50 references — full list in the complete paper: https://tomesphere.com/paper/PMC12782339/full.md

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Source: https://tomesphere.com/paper/PMC12782339