# Preventing Laryngeal Nerve Palsy During Thyroidectomies: A Non-systematic Review of the Surgical Anatomy Literature

**Authors:** Shahzeb Sheikh, James Moor

PMC · DOI: 10.7759/cureus.98801 · Cureus · 2025-12-09

## TL;DR

This review examines how anatomical variations and surgical techniques affect the risk of nerve damage during thyroid surgery.

## Contribution

The paper highlights the clinical relevance of specific anatomical landmarks and variations in preventing recurrent laryngeal nerve injury.

## Key findings

- Recurrent laryngeal nerve injury is linked to factors like repeat surgeries and malignancy.
- Extralaryngeal branching increases the risk of RLN injury during thyroidectomy.
- Anatomical landmarks like the Zuckerkandl tubercle have greater clinical utility than the inferior thyroid artery.

## Abstract

This non-systematic review explored recurrent laryngeal nerve (RLN) injury mechanisms, anatomical landmarks, and extralaryngeal branching (ELB) variations during thyroidectomy. A PubMed and Medline search identified relevant studies, including systematic reviews and meta-analyses. Key risk factors for RLN palsy include repeat surgeries, extent of resection, and malignancy. Injury mechanisms involve traction, compression, and thermal damage. The Zuckerkandl tubercle and Berry’s ligament show consistent RLN relationships with greater clinical utility than the inferior thyroid artery. ELB, especially bifurcation, increases RLN injury risk. Understanding RLN anatomy and variations is crucial to minimizing injury. Further studies are needed to assess the clinical significance of these anatomical landmarks and variations to guide safer surgeries.

## Linked entities

- **Diseases:** malignancy (MONDO:0004992)

## Full-text entities

- **Diseases:** Injury (MESH:D014947), RLN (MESH:D061226), malignancy (MESH:D009369), Laryngeal Nerve Palsy (MESH:D014826)

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12782130/full.md

## References

94 references — full list in the complete paper: https://tomesphere.com/paper/PMC12782130/full.md

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Source: https://tomesphere.com/paper/PMC12782130