# Biopsy of the Superficial Sensory Radial Nerve in the Distal Forearm: A Technical Note

**Authors:** Alexander E Shearin, Daniel Surdell

PMC · DOI: 10.7759/cureus.98796 · Cureus · 2025-12-09

## TL;DR

This paper provides a technical guide for biopsying the superficial sensory radial nerve in the forearm, useful for diagnosing nerve-related conditions.

## Contribution

The paper introduces a specific technique for SSRN biopsy in the distal forearm, offering a practical alternative for upper extremity nerve pathology.

## Key findings

- The superficial sensory radial nerve is accessible in the distal forearm between specific tendons.
- The described technique allows for effective nerve biopsy in upper extremity conditions.

## Abstract

Neurosurgeons are frequently consulted for nerve biopsy. Common indications for nerve biopsy include vasculitis, peripheral neuropathy of unknown etiology, amyloidosis, and chronic inflammatory demyelinating polyneuropathy (CIDP). While the sural nerve is most commonly selected, a specimen from the superficial sensory radial nerve (SSRN) is often chosen when the pathology is confined to the upper extremities. The SSRN is typically exposed in the proximal forearm between the brachioradialis (BR) and extensor carpi radialis longus (ECRL) tendons. Here, we describe the technical details for biopsy of the SSRN in the distal forearm, where the nerve is superficially located.

## Linked entities

- **Diseases:** vasculitis (MONDO:0018882), peripheral neuropathy (MONDO:0003620), amyloidosis (MONDO:0019065)

## Full-text entities

- **Diseases:** CIDP (MESH:D020277), amyloidosis (MESH:D000686), peripheral neuropathy (MESH:D010523), vasculitis (MESH:D014657)

## Full text

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## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12782050/full.md

## References

17 references — full list in the complete paper: https://tomesphere.com/paper/PMC12782050/full.md

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Source: https://tomesphere.com/paper/PMC12782050