# Hallux gangrene following first metatarsophalangeal arthrodesis

**Authors:** Nicholas Frappa, Danil Chernov, Morgan Dillon, Matthew G Alben, Josh Slowinski, Gabrielle Hartman, Jennifer Gurske-dePerio

PMC · DOI: 10.1093/jscr/rjaf1060 · Journal of Surgical Case Reports · 2026-01-08

## TL;DR

A rare case of toe gangrene after foot surgery in a woman with celiac disease highlights possible microvascular complications.

## Contribution

Reports a rare postoperative complication linked to autoimmune disease despite absence of typical vascular risk factors.

## Key findings

- A 44-year-old woman with celiac disease developed gangrene after MTP arthrodesis despite normal vascular pulses.
- Angiography showed no proximal obstruction, suggesting a microvascular cause like vasospasm or autoimmune vasculitis.
- The case emphasizes the need for early detection of digital ischemia after foot surgery in patients with autoimmune conditions.

## Abstract

Hallux rigidus is commonly treated with first metatarsophalangeal (MTP) arthrodesis, a procedure with high success and low complication rates. We present a rare case of postoperative hallux gangrene following first MTP arthrodesis in a 44-year-old woman with celiac disease and no conventional vascular risk factors. Despite normal dorsalis pedis and posterior tibial pulses, the great toe developed ischemic changes on postoperative Day 1, progressing to dry gangrene requiring amputation at the MTP joint. Angiography revealed no proximal obstruction, supporting a microvascular etiology. Potential mechanisms include vasospasm, small-vessel thrombosis or autoimmune-mediated vasculitis. This case underscores the importance of early recognition of digital ischemia after forefoot surgery, even in healthy patients, and highlights the possible role of autoimmune disease in postoperative microvascular compromise.

## Linked entities

- **Diseases:** celiac disease (MONDO:0005130)

## Full-text entities

- **Diseases:** autoimmune disease (MESH:D001327), autoimmune-mediated (MESH:C567355), vasculitis (MESH:D014657), vasospasm (MESH:D020301), digital ischemia (MESH:D007511), Hallux gangrene (MESH:D005734), ischemic (MESH:D002545), small-vessel thrombosis (MESH:D059345), Hallux rigidus (MESH:D020859), celiac disease (MESH:D002446)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12782014/full.md

## References

14 references — full list in the complete paper: https://tomesphere.com/paper/PMC12782014/full.md

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Source: https://tomesphere.com/paper/PMC12782014