# Noninfectious Necrotizing Aortitis With Predominantly Neutrophilic Infiltrate

**Authors:** Nathan A. Williams, Mark Colantonio, Anastasia Miller, Allen P. Burke

PMC · DOI: 10.1155/crip/5727208 · Case Reports in Pathology · 2026-01-08

## TL;DR

This paper reports a rare case of noninfectious aortitis in a young man, showing that a neutrophilic infiltrate can occur without infection.

## Contribution

The novelty lies in demonstrating that noninfectious aortitis can present with a neutrophilic infiltrate, challenging assumptions about its causes.

## Key findings

- A case of noninfectious ascending aortitis was identified in a young, previously healthy man.
- Histopathological analysis revealed a predominantly neutrophilic infiltrate without evidence of infection.

## Abstract

Aortitis can be either infectious or noninfectious, and cases of noninfectious aortitis are not well understood. Our study presents a case of noninfectious ascending aortitis in a relatively young, previously healthy man, characterized by a predominantly neutrophilic infiltrate on histopathological examination without an inciting microorganism. This case report highlights that a neutrophilic infiltrate does not necessarily indicate an infectious etiology in ascending aortic aneurysms.

## Linked entities

- **Diseases:** aortitis (MONDO:0006656)

## Full-text entities

- **Diseases:** Aortitis (MESH:D001025), ascending aortic aneurysms (MESH:D000094625)

## Full text

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## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC12780741/full.md

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Source: https://tomesphere.com/paper/PMC12780741