# A Case of Post‐Transplantation Lymphoproliferative Disorder Following Kidney Transplantation

**Authors:** Punam Ajay Raval, John Otieno Odhiambo, Hanika Patel, Ahmed Sokwala

PMC · DOI: 10.1155/crin/5917161 · Case Reports in Nephrology · 2026-01-08

## TL;DR

A 65-year-old kidney transplant patient developed a rare lymphoma tumor in his intestine, which was diagnosed and surgically removed.

## Contribution

This case highlights post-transplant lymphoproliferative disorder as a rare complication following kidney transplantation.

## Key findings

- A midjejunal tumor was found to be diffuse large B-cell lymphoma in a kidney transplant recipient.
- The patient's symptoms included abdominal pain, vomiting, and constipation due to bowel obstruction.
- Histological analysis confirmed the tumor as lymphoproliferative in origin.

## Abstract

This was a case of a 65‐year‐old gentleman known to have diabetes mellitus and hypertension since 2012 and post renal transplantation in 2016. He had also been treated for hepatitis C infection in the past. His regular medications included nebivolol 5 mg once a day, tacrolimus 4 mg twice a day, mycophenolate mofetil 500 mg twice a day, prednisolone 5 mg once a day, and insulin–novomix 14 units in the morning and 6 units at night. He presented to a tertiary teaching hospital in Kenya in October 2023 with abdominal pain, vomiting, and constipation on and off for 6 months, worse in the month prior to presentation. His examination was positive for dehydration, abdominal distension, and generalized abdominal tenderness. He had a normal hematological profile and renal function. A CT scan of the abdomen showed features of small bowel obstruction from the distal ileal to distal jejunal bowel loops. The patient underwent an exploratory laparotomy with intraoperative findings of a midjejunal tumor completely obstructing the lumen with proximal dilatation. The tumor was subsequently excised. Histological specimen confirmed diffuse large B‐cell lymphoma (DLBCL) as his final diagnosis.

## Linked entities

- **Diseases:** diabetes mellitus (MONDO:0005015), hepatitis C infection (MONDO:0005231), diffuse large B-cell lymphoma (MONDO:0018905)

## Full-text entities

- **Diseases:** abdominal distension (MESH:D000007), tumor (MESH:D009369), constipation (MESH:D003248), dehydration (MESH:D003681), diabetes mellitus (MESH:D003920), Lymphoproliferative Disorder (MESH:D008232), hepatitis C infection (MESH:D006526), DLBCL (MESH:D016403), hypertension (MESH:D006973), abdominal pain (MESH:D015746), small bowel obstruction (MESH:D007409), vomiting (MESH:D014839)
- **Chemicals:** mycophenolate mofetil (MESH:D009173), prednisolone (MESH:D011239), novomix (-), tacrolimus (MESH:D016559), nebivolol (MESH:D000068577), insulin (MESH:D007328)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

8 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12780540/full.md

## References

11 references — full list in the complete paper: https://tomesphere.com/paper/PMC12780540/full.md

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Source: https://tomesphere.com/paper/PMC12780540