# Primary human intestinal organoids with biallelic UNC45A variants suggest role of cystic fibrosis transmembrane conductance regulator in pathogenesis of UNC45A‐related intestinal disorder

**Authors:** April Rose Foster, Natasha G., Rebecca Harris, Matthias Zilbauer, Alexander Ross

PMC · DOI: 10.1002/jpn3.70230 · Journal of Pediatric Gastroenterology and Nutrition · 2025-10-17

## Full-text entities

- **Genes:** CFTR (CF transmembrane conductance regulator) [NCBI Gene 1080] {aka ABC35, ABCC7, CF, CFTR/MRP, MRP7, TNR-CFTR}, UNC45A (unc-45 myosin chaperone A) [NCBI Gene 55898] {aka GC-UNC45, GCUNC-45, GCUNC45, IRO039700, OOHE, SMAP-1}
- **Diseases:** intestinal disorder (MESH:D007410)
- **Species:** Homo sapiens (human, species) [taxon 9606]

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## References

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Source: https://tomesphere.com/paper/PMC12780477