# Designing network based intervention strategies for epidemics of infectious diseases from edge based infection probability

**Authors:** Veronika Halász, Joacim Rocklöv

PMC · DOI: 10.1038/s41598-025-33300-3 · Scientific Reports · 2026-01-06

## TL;DR

This paper explores how different types of human contacts influence the spread of infectious diseases and suggests focusing on high-risk connections to control epidemics.

## Contribution

The study introduces a novel approach to identifying critical contact types in social networks that can curb epidemics when restricted.

## Key findings

- Restricting contacts that bridge clusters or communities can effectively curb epidemics.
- Contacts with high transmission probability are particularly important to target for intervention.
- Balancing transmission control with social and economic stability is achievable by focusing on specific contact types.

## Abstract

Epidemics underscore the critical role of human contact networks in shaping the spread of infectious diseases. Transmission varies depending on a range of factors, including virus characteristics, the type and duration of contact, and whether it occurs indoors or outdoors. However, not only does the probability of transmission differ, but the impact of each transmission event depends on the ability of a single event to spread the virus to new, previously unaffected, socially segmented groups in society. Effective policymaking should be guided by a nuanced understanding of how infections spread, ensuring that interventions are proportional to the risks they aim to address. In this study, we conducted a series of theoretical experiments on generated networks that are structurally similar to real social contact networks. Using models that distinguish between regular, repeated contacts and occasional, random, or transient contacts, we simulated fictitious epidemics on different sample graphs with varying contact restrictions and then compared their trajectories. Based on the observed differences, we identified the contact types whose restriction can effectively curb the epidemic. We find that it is particularly important to focus on relationships that form a bridge between clusters or communities and on contacts with particularly high transmission probability. By doing so, public health efforts can more effectively balance the dual goals of minimizing transmission and maintaining social and economic stability.

## Full-text entities

- **Diseases:** infectious diseases (MESH:D003141), infection (MESH:D007239)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12780171/full.md

## References

2 references — full list in the complete paper: https://tomesphere.com/paper/PMC12780171/full.md

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Source: https://tomesphere.com/paper/PMC12780171