A Rare Case of Sarcoidosis Presenting With Endobronchial Mass

TL;DR

A 34-year-old man with sarcoidosis presented with a rare endobronchial mass, highlighting the importance of considering this condition in differential diagnoses.

Contribution

This paper presents a rare clinical case of sarcoidosis manifesting as an endobronchial mass, emphasizing diagnostic challenges and management.

Findings

Sarcoidosis can present as an endobronchial mass, mimicking malignancy.

Histopathological findings showed granulomatous inflammation without necrosis or malignancy.

The patient was successfully treated with oral prednisolone after diagnosis.

Abstract

We report a rare case of sarcoidosis presenting with endobronchial mass in a 34-year-old male patient who presented with progressive shortness of breath and non-productive cough for one month. It is diagnostically challenging due to its non-specific presentations, as mass lesions can mimic malignancy. In this case, CT chest initially revealed mediastinal lymphadenopathy, multiple small peripheral lung nodules and mild right sided pleural effusion. Positron emission tomography (PET) CT revealed mediastinal lymphadenopathy and bilateral subpleural nodules. Bronchoscopy revealed a polypoid mass with a broad base in segmental bronchus of the right lower lobe. Histopathological examination of biopsy revealed granulomatous inflammation with lymphoplasmacytic infiltration, with no evidence of necrosis or malignancy. The endobronchial mass was removed using electrosurgical snaring with cryoextraction. Microbiological and cytology examinations were unremarkable. The patient was diagnosed with sarcoidosis and was initiated on oral prednisolone. This case highlights the importance of considering sarcoidosis in the differential diagnosis to ensure timely and appropriate management.

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