# Representation and generalizability in clinical research: Back to basics

**Authors:** Shari Messinger, Ann Brearley, Barbara H. Brumbach, Manisha Desai, Felicity T. Enders, Jodi Lapidus, Mary Sammel, Heidi M. Spratt

PMC · DOI: 10.1017/cts.2025.10202 · 2025-11-28

## Full-text entities

- **Genes:** G6PD (glucose-6-phosphate dehydrogenase) [NCBI Gene 2539] {aka CNSHA1, G6PD1}
- **Diseases:** stroke (MESH:D020521), coronary heart disease (MESH:D003327), pain (MESH:D010146), cancer (MESH:D009369), hemolytic anemia (MESH:D000743), malaria (MESH:D008288), G6PD deficiency (MESH:D005955), joint pain (MESH:D018771)
- **Chemicals:** warfarin (MESH:D014859)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12779481/full.md

---
Source: https://tomesphere.com/paper/PMC12779481