White-tailed deer population declines in a high-prevalence chronic wasting disease region of Arkansas, USA
Heather E. Gaya, Marcelo H. Jorge, Lisa A. Jorge, Mark G. Ruder, Gino J. D’Angelo, Richard B. Chandler, Michael J. Chamberlain, Byron Caughey, Byron Caughey, Byron Caughey, Byron Caughey

TL;DR
This study shows that chronic wasting disease in deer leads to population declines in Arkansas, with males being more affected than females.
Contribution
The study provides empirical evidence of CWD's impact on deer population viability through long-term density monitoring.
Findings
Deer densities declined by an average of 17% per year across three study sites.
Male deer densities declined faster (23% per year) than female deer (15% per year).
Current harvest regulations may not be sustainable for the studied deer populations.
Abstract
Chronic wasting disease (CWD) is a fatal transmissible spongiform encephalopathy affecting cervids worldwide. CWD was first detected in Arkansas in 2015 and as of August 2025 has been detected in 24 counties across the state. Within the Tier 1 CWD management zone of northern Arkansas, average apparent CWD prevalence exceeded 25% at the onset of our study in 2021. We tested the hypothesis that high prevalence of CWD negatively affects white-tailed deer population viability. We collected data from 243 camera traps and deployed GPS-collars on 131 adult deer to monitor population dynamics. Using spatial mark-resight models, we estimated density of adult deer from 2021 to 2024 at three sites across a presumed CWD gradient to assess the impacts of high CWD prevalence on deer abundance. Deer densities declined at all three study sites, at an average 17% (95% CI: 8% − 24%) decline per year.…
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Taxonomy
TopicsPrion Diseases and Protein Misfolding · Salmonella and Campylobacter epidemiology · Genetic Mapping and Diversity in Plants and Animals
