Prolonged Postoperative Paralysis Following Elective Tonsillectomy: A Case of Pseudocholinesterase Deficiency
Kade Walsh, Shane Smith, Gabriella Manilla, Jatin Ahluwalia, Robert Stachler

TL;DR
A 19-year-old man experienced prolonged paralysis after surgery due to a rare enzyme deficiency, highlighting the importance of recognizing this condition in medical care.
Contribution
This case report adds to the understanding of pseudocholinesterase deficiency and its impact on postoperative recovery.
Findings
The patient experienced prolonged postoperative paralysis after tonsillectomy.
Pseudocholinesterase deficiency was suspected as the underlying cause.
The case emphasizes the need for awareness and management strategies for this rare condition.
Abstract
Pseudocholinesterase deficiency is a rare disorder of the enzyme butyrylcholinesterase that can lead to delayed emergence following exposure to depolarizing neuromuscular blocking agents. We report the case of a 19-year-old male who underwent elective tonsillectomy and experienced prolonged postoperative paralysis, suspected to be due to pseudocholinesterase deficiency. The patient had no significant past medical history or family history of the condition. This report highlights the clinical implications of pseudocholinesterase deficiency and discusses strategies for perioperative management.
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
Peer Reviews
No public reviews on file for this paper yet. If you reviewed it on a platform where reviews are public (OpenReview, ICLR, NeurIPS, ICML), you can paste yours below so the community can read it here.
Videos
No videos yet. Explain this paper in a talk, walkthrough, or lecture? Add one.
Taxonomy
TopicsCholinesterase and Neurodegenerative Diseases · Pesticide Exposure and Toxicity · Intensive Care Unit Cognitive Disorders
