# Hypertrophic Pyloric Stenosis in a Four-Week-Old Infant: Radiological Diagnosis and Pitfalls

**Authors:** Biraj Pokhrel, Aaraju Bhatta, Anil Basnet, Niraaz Pokhrel, Dosti Regmi

PMC · DOI: 10.7759/cureus.98606 · 2025-12-06

## TL;DR

This paper discusses the diagnosis and treatment of a four-week-old infant with a stomach condition causing vomiting, highlighting the importance of ultrasound imaging.

## Contribution

The paper presents a case emphasizing the role of ultrasonography in diagnosing infantile hypertrophic pyloric stenosis and highlights imaging pitfalls.

## Key findings

- Ultrasonography confirmed the diagnosis of infantile hypertrophic pyloric stenosis in a four-week-old infant.
- The case underscores the importance of recognizing imaging pitfalls like a posteriorly displaced pylorus.
- The patient was successfully treated with fluid resuscitation and a Ramstedt pyloromyotomy.

## Abstract

Infantile hypertrophic pyloric stenosis (IHPS) is a common acquired condition of infancy, characterized by pyloric muscle hypertrophy leading to complete or near-complete gastric outlet obstruction. A typical presentation includes projectile, non-bilious vomiting. While the palpable "olive" and visible peristaltic waves are classic signs, ultrasonography is the diagnostic modality of choice due to its high accuracy. Diagnosis relies on established sonographic thresholds for pyloric muscle thickness and canal length. Differential diagnoses include transient pylorospasm, which resolves on its own, and prostaglandin-induced mucosal hypertrophy, where only the muscular wall should be measured. Herein, we present the case of a four-week-old male infant with projectile non-bilious vomiting and failure to thrive. Ultrasonography confirmed the diagnosis, demonstrating the classic radiological signs. The patient was successfully managed with fluid resuscitation and a Ramstedt pyloromyotomy. This case highlights the pivotal role of ultrasonography in diagnosing IHPS, discusses relevant differential diagnoses, and underscores the importance of recognizing potential imaging pitfalls, such as a posteriorly displaced pylorus due to an overdistended stomach.

## Linked entities

- **Diseases:** infantile hypertrophic pyloric stenosis (MONDO:0001560)

## Full-text entities

- **Diseases:** vomiting (MESH:D014839), failure to thrive (MESH:D005183), Hypertrophic Pyloric Stenosis (MESH:D046248), gastric outlet obstruction (MESH:D017219), pyloric muscle hypertrophy (MESH:C536106), mucosal hypertrophy (MESH:D006984)
- **Chemicals:** prostaglandin (MESH:D011453)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12776224/full.md

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Source: https://tomesphere.com/paper/PMC12776224