# Reply

**Authors:** Reina Hara, Yoshito Takeda

PMC · DOI: 10.1016/j.jacig.2025.100615 · 2025-11-21

## Full-text entities

- **Genes:** IGHE (immunoglobulin heavy constant epsilon) [NCBI Gene 3497] {aka IgE}
- **Diseases:** allergy (MESH:D004342), asthma (MESH:D001249), airway inflammation (MESH:D007249), respiratory diseases (MESH:D012140)

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Source: https://tomesphere.com/paper/PMC12775930