# Comparative evaluation of flat-panel volume CT protocols for high-resolution visualization of middle ear anatomy in human skull specimens

**Authors:** Franz-Tassilo Müller-Graff, Jan von Düring, Bjoern Spahn, Stefan Weick, Anne Richter, Jan-Peter Grunz, Tilmann Neun, Stephan Hackenberg, Kristen Rak

PMC · DOI: 10.1038/s41598-025-33592-5 · 2026-01-05

## TL;DR

This study compares different CT scan protocols for imaging the middle ear, finding that one protocol offers the best balance between image quality and radiation safety.

## Contribution

The study introduces a comparative evaluation of flat-panel volume CT protocols for middle ear imaging in human skulls.

## Key findings

- Protocols 14s I and 8s I achieved the highest image quality for middle ear structures.
- The 8s I protocol provided optimal balance between image quality and radiation safety.
- Shorter protocols like 4s I reduced radiation but failed to consistently meet clinical standards.

## Abstract

This study evaluates the imaging quality and radiation dose of six flat-panel volume CT protocols with varying technical parameters, including examination time (“Artis Icono” angiography system (Siemens Healthcare AG, Erlangen, Germany): 14s DCT HEAD MICRO CARE (14s I), 14s DCT HEAD MICRO CARE 4 (14s II), 8s DCT HEAD 70kV CARE 1 (8s I), 8s DCT HEAD 70kV CARE 3 (8s II), 4s DCT HEAD CARE FB (4s I), 4s DCT HEAD CARE FB 2 (4s II)) for middle ear visualization in human skull specimens. A scoring system assessed the delineation of 28 anatomical structures, narrowed to eight for detailed evaluation. Protocols 14s I and 8s I achieved the highest image quality, exceeding the clinical threshold. 8s I protocol demonstrated an optimal balance between image quality and radiation safety, adhering to the ALADA principle (“as low as diagnostically acceptable”). While 14s I offered superior detail, it involved higher radiation exposure without substantial further image improvement, indicating a saturation effect. Shorter protocols, such as 4s I, offered radiation-sparing advantages but did not consistently meet clinical image quality standards. Protocol 8s I is recommended as the standard for middle ear imaging, with 4s I as a potential alternative for cases requiring minimized radiation exposure and reduced motion artifact susceptibility.

The online version contains supplementary material available at 10.1038/s41598-025-33592-5.

## Full-text entities

- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12775453/full.md

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Source: https://tomesphere.com/paper/PMC12775453