# Hyperspectral image and chemometrics. A step beyond classical spectroscopic PAT tools

**Authors:** Anna de Juan, Rodrigo Rocha de Oliveira

PMC · DOI: 10.1007/s00216-025-06154-x · Analytical and Bioanalytical Chemistry · 2025-10-28

## TL;DR

This paper explores how hyperspectral imaging combined with chemometrics can improve process analytical technology by providing detailed spatial and chemical information.

## Contribution

The paper highlights novel applications of hyperspectral imaging and chemometrics in solving PAT challenges.

## Key findings

- HSI provides richer spatial and chemical data than traditional spectroscopy.
- HSI combined with chemometrics can address diverse PAT challenges.
- Dedicated chemometric tools are essential for interpreting HSI data in PAT contexts.

## Abstract

Hyperspectral imaging (HSI) is a very complete analytical measurement that encloses rich spatial and chemical information. This double side enables HSI to outperform classical spectroscopic measurements and vision systems based only on color information. However, HSI requires powerful data analysis tools for interpretation and to facilitate its implementation in process analytical technology (PAT) contexts. This work is a brief perspective that shows a diversity of PAT challenges that can be solved with the combined use of HSI and dedicated chemometric procedures.

## Full-text entities

- **Diseases:** HSI (MESH:C564543)
- **Chemicals:** PA6 (MESH:C009916), PP (MESH:D011126), ABS (-), CA (MESH:D019343), S (MESH:D013455), PS (MESH:D011137), ASA (MESH:D001241), C (MESH:D002244), PBT (MESH:C041733), SSG (MESH:C048390)
- **Species:** Chenopodium quinoa (quinoa, species) [taxon 63459]

## Full text

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## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12775029/full.md

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Source: https://tomesphere.com/paper/PMC12775029