# Secondary intention healing with biodegradable temporizing matrix (BTM) in a comorbid patient: A case report

**Authors:** Ho Yin Kam, Yuet Ching Wong, Stephen Goldie

PMC · DOI: 10.1016/j.jpra.2025.11.020 · JPRAS Open · 2025-11-23

## TL;DR

A biodegradable material helped heal a complex wound in a patient who previously failed traditional treatments.

## Contribution

This case demonstrates BTM's effectiveness in secondary healing for high-risk patients with impaired healing.

## Key findings

- BTM facilitated healing by secondary intention in an infected scalp wound.
- Granulation and neodermis formation eliminated the need for a second-stage graft.
- BTM shows promise for complex wounds when conventional methods fail.

## Abstract

Biodegradable temporizing matrix (BTM) is a synthetic dermal substitute designed for complex wound reconstruction, typically in a two-stage process. We present a case involving BTM-assisted healing by secondary intention of an infected scalp wound in a medically complex patient following failed split-thickness skin grafting. Owing to substantial granulation and neodermis formation, the planned second-stage grafting was ultimately deemed unnecessary. This case highlights BTM’s potential as a definitive reconstructive option in high-risk patients with impaired healing capacity and supports its role in managing complex wounds, particularly when conventional reconstructive strategies are contraindicated or have failed.

## Full-text entities

- **Diseases:** infected (MESH:D007239)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC12774673/full.md

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Source: https://tomesphere.com/paper/PMC12774673