# Unilateral Parietal Bone Thickening in a Young Female Donor With a History of a Malignant Brain Neoplasm

## TL;DR

A young female donor with a history of brain cancer showed thickening in one parietal bone, likely due to tumor-related bone activity.

## Contribution

This case highlights post-mortem bony changes as a potential indicator of intracranial disease.

## Key findings

- Unilateral thickening of the right parietal bone was observed in a 21-year-old female cadaver.
- The thickened bone measured 7.2 mm, exceeding normal thickness and likely linked to osteoblastic tumor activity.
- No other skeletal abnormalities were found, supporting a localized tumor-related cause.

## Abstract

Calvarial thickening can occur as a reaction to various intracranial conditions, most commonly due to chronic pressure from adjacent mass lesions. We report the case of a 21-year-old female cadaver found to have unilateral thickening of the right parietal bone during routine anatomy lab dissection. The available medical history noted a malignant brain tumor. Measurements showed the right parietal bone to be 7.2 mm thick, which is greater than what is considered normal. No other skeletal abnormalities were noted. The isolated thickening is most consistent with tumor-related osteoblastic activity. This case underscores the value of examining post-mortem bony changes to better understand intracranial disease.