# Serratia marcescens-Induced Pericarditis Leading to Rapid-Onset Cardiac Tamponade in a Patient With Underlying Malignancy

**Authors:** Ashirbad Acharya, Anurag Karki, Narayan Bhurtel, Simran Pradhan, Puja Thapa, Yogesh Pandey, Suraj Shrestha, Ricardo Conti

PMC · DOI: 10.7759/cureus.98656 · Cureus · 2025-12-07

## TL;DR

A rare case of Serratia marcescens causing pericarditis and cardiac tamponade in a cancer patient is reported, highlighting the need for early detection and targeted treatment.

## Contribution

This paper presents a rare clinical case of Serratia marcescens-induced pericarditis leading to tamponade in a patient with malignancy.

## Key findings

- Serratia marcescens was identified in pericardial fluid cultures.
- The patient was successfully treated with drainage and antibiotics.
- The case underscores the importance of considering rare pathogens in high-risk patients.

## Abstract

Serratia marcescens is a Gram-negative bacterium that mostly causes urinary tract infections, respiratory infections, and catheter-related bloodstream infections. It rarely causes pericarditis, especially leading to tamponade, which is exceptionally rare. We describe a case that had a history of intravenous drug usage and presented with dyspnea and chest pain. Small cell lung carcinoma and a newly developed moderate pericardial effusion with echocardiographic indications of imminent tamponade were discovered during imaging. Pericardial fluid cultures identified Serratia marcescens. The patient was treated successfully with pericardial fluid drainage followed by antibiotics. This case emphasizes the importance of considering unusual organisms like S. marcescens when treating pericardial infections, particularly in patients who are at high risk. Early identification and focused treatment are crucial for the management of complications like cardiac tamponade.

## Linked entities

- **Diseases:** pericarditis (MONDO:0005904), cardiac tamponade (MONDO:0001297), small cell lung carcinoma (MONDO:0008433)
- **Species:** Serratia marcescens (taxon 615)

## Full-text entities

- **Diseases:** pericardial effusion (MESH:D010490), Pericarditis (MESH:D010493), respiratory infections (MESH:D012141), pericardial infections (MESH:D007239), urinary tract infections (MESH:D014552), bloodstream infections (MESH:D018805), Cardiac Tamponade (MESH:D002305), dyspnea (MESH:D004417), chest pain (MESH:D002637), Small cell lung carcinoma (MESH:D055752)
- **Species:** Serratia marcescens (species) [taxon 615], Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

13 references — full list in the complete paper: https://tomesphere.com/paper/PMC12774549/full.md

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Source: https://tomesphere.com/paper/PMC12774549