# A Case of Lung Cancer Unexpectedly Detected with 99m Tc (V)-DMSA Whole-Body/SPECT Imaging

## TL;DR

A 65-year-old woman's lung cancer was unexpectedly detected using 99m Tc (V)-DMSA imaging, which showed abnormal uptake in lung masses.

## Contribution

Demonstrates the effectiveness of 99m Tc (V)-DMSA imaging in detecting lung cancer through abnormal radiotracer uptake.

## Key findings

- 99m Tc (V)-DMSA imaging revealed abnormal uptake in lung lesions.
- The imaging findings were confirmed by biopsy and bronchial washing cytology as non-small cell lung cancer.

## Abstract

In terms of cancer-related deaths, lung cancer is the most common type. To prevent this malignant and dangerous disease from progressing, early and differential diagnoses are very critical. A combination of dimercaptosuccinic acid and pentavalent
99m
Tc under alkaline conditions,
99m
Tc (V)-DMSA, can be used for malignant tumors' early diagnosis and prognosis. The
99m
Tc (V)-DMSA radiotracer is most commonly used for follow-up of medullary thyroid cancer metastases, but it is also successful in lung cancer and other malignancies. In this case, a 65-year-old woman with a recent history of nonproductive cough and mild dyspnea and suspicious small masses of lungs in computed tomography was selected for imaging with
99m
Tc (V)-DMSA to evaluate the condition of radiotracer uptake in the lung masses. The whole-body and single-photon emission computed tomography imaging with semiquantitative analysis showed abnormal uptakes in the lesions and the patient underwent to transbronchial biopsy and bronchial washing cytology that confirmed non-small cell lung cancer.