# Surgical Resection with Posterior Rectus Sheath Preservation and Mesh Reconstruction without Pursuing Wide Negative Margins for an Abdominal Wall Desmoid in Familial Adenomatous Polyposis: A Case Report

**Authors:** Makoto Hasegawa, Tomoyuki Momma, Erina Suzuki, Yuko Hashimoto, Hiroki Yago, Misato Ito, Takuro Matsumoto, Daisuke Ujiie, Shun Chida, Hirokazu Okayama, Motonobu Saito, Wataru Sakamoto, Koji Kono

PMC · DOI: 10.70352/scrj.cr.25-0584 · Surgical Case Reports · 2025-12-26

## TL;DR

A 48-year-old man with FAP had successful surgery for an abdominal wall desmoid tumor without wide margins, using mesh for reconstruction and achieving no recurrence after 9 months.

## Contribution

Demonstrates feasibility of limited-margin surgery with mesh for FAP-related desmoid tumors, avoiding wide resection while maintaining function.

## Key findings

- The tumor was resected with microscopically negative (R0) margins without wide excision.
- No recurrence was observed at 9 months post-surgery.
- Mesh reconstruction preserved abdominal wall function without complications.

## Abstract

Desmoid tumors are locally aggressive, non-metastatic neoplasms that develop in up to 20% of patients with familial adenomatous polyposis (FAP). While active surveillance is the initial approach, surgery may be indicated for symptomatic or progressive disease; however, the optimal surgical strategy remains debated.

We present the case of a 48-year-old man with FAP and a history of two previous laparotomies. He developed a progressive and symptomatic abdominal wall desmoid tumor refractory to non-operative management, including medical therapy. He underwent a surgical resection without pursuing wide negative margins. Intraoperatively, the tumor was adherent to the prior midline incision scar and anterior rectus sheath. After resection, the resulting 100 × 50 mm fascial defect was repaired with a synthetic mesh. Histopathology confirmed the desmoid tumor with microscopically negative (R0) resection margins, and no evidence of recurrence was observed at the 9-month follow-up.

Surgical resection without pursuing wide negative margins, previously described in sporadic desmoids, may be considered a feasible option for selected FAP-associated abdominal wall tumors, balancing local control with no apparent postoperative abdominal wall functional deficit.

## Linked entities

- **Diseases:** familial adenomatous polyposis (MONDO:0021055)

## Full-text entities

- **Diseases:** FAP (MESH:D011125), Desmoid tumors (MESH:C535944), neoplasms (MESH:D009369)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

17 references — full list in the complete paper: https://tomesphere.com/paper/PMC12774478/full.md

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Source: https://tomesphere.com/paper/PMC12774478