# Clinical Spectrum of Hemolytic Anemia in Loxoscelism: Report of Two Cases Highlighting Variable Severity and Management

**Authors:** Anas Al-Sadi, Aakriti Adhikari, Israa Jawarneh, Elrazi Ali, Anuj Shrestha

PMC · DOI: 10.1155/crh/9200571 · Case Reports in Hematology · 2026-01-05

## TL;DR

This paper reports two cases of hemolytic anemia caused by brown recluse spider bites, showing different severities and treatment approaches.

## Contribution

The study highlights variable clinical presentations and treatment options for loxoscelism-mediated hemolysis based on severity and pathophysiology.

## Key findings

- Loxoscelism can lead to life-threatening hemolytic anemia.
- Clinical presentations and management of loxoscelism vary based on severity and pathophysiology.

## Abstract

Loxoscelism can cause local as well as systemic manifestations. Hematologic complications of brown recluse spider venom can be life‐threatening. Here, we present two cases of loxoscelism‐mediated hemolysis that highlight the variable clinical presentations and treatment options available based on severity and pathophysiology of hemolysis.

## Linked entities

- **Diseases:** hemolytic anemia (MONDO:0003664)

## Full-text entities

- **Diseases:** Hemolytic Anemia (MESH:D000743), hemolysis (MESH:D006461)
- **Chemicals:** loxoscelism (-)

## Full text

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## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12771651/full.md

## References

17 references — full list in the complete paper: https://tomesphere.com/paper/PMC12771651/full.md

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Source: https://tomesphere.com/paper/PMC12771651